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Jatropholone A

PubChem CID: 14059526

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Compound Synonyms Jatropholone A, 71424-66-3, (4S,10R,12S)-7-hydroxy-4,8,11,11-tetramethyl-15-methylidenetetracyclo[7.6.0.02,6.010,12]pentadeca-1,6,8-trien-3-one, CCRIS 1441, CHEMBL4214497, AKOS040752166, 6H-Cyclopropa(3,4)cyclohept(1,2-e)inden-6-one, 1,1a,4,5,7,8,9,9a-octahydro-3-hydroxy-1,1,2,5-tetramethyl-7-methylene-, (1aR,5S,9aS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CCC3C4CC4CCC(C)C3C12
Np Classifier Class Jatropholane diterpenoids
Deep Smiles C[C@H]CccC5=O))cC=C)CC[C@H][C@@H]c7cc%11O))C)))C3C)C
Heavy Atom Count 22.0
Classyfire Class Indanes
Scaffold Graph Node Level CC1CCC2CC2C2CCC3CCC(O)C3C12
Classyfire Subclass Indanones
Isotope Atom Count 0.0
Molecular Complexity 534.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (4S,10R,12S)-7-hydroxy-4,8,11,11-tetramethyl-15-methylidenetetracyclo[7.6.0.02,6.010,12]pentadeca-1,6,8-trien-3-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 4.5
Gsk 4 400 Rule False
Molecular Formula C20H24O2
Scaffold Graph Node Bond Level C=C1CCC2CC2c2ccc3c(c21)C(=O)CC3
Prediction Swissadme 0.0
Inchi Key BMHPRIPRPDSKRK-SVKFGRERSA-N
Silicos It Class Moderately soluble
Fcsp3 0.55
Logs -5.825
Rotatable Bond Count 0.0
Logd 3.977
Synonyms jatropholone a, jatropholones a
Esol Class Moderately soluble
Functional Groups cC(=C)C, cC(C)=O, cO
Compound Name Jatropholone A
Prediction Hob Swissadme 0.0
Exact Mass 296.178
Formal Charge 0.0
Monoisotopic Mass 296.178
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 296.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.708260181818182
Inchi InChI=1S/C20H24O2/c1-9-6-7-13-17(20(13,4)5)15-11(3)19(22)12-8-10(2)18(21)16(12)14(9)15/h10,13,17,22H,1,6-8H2,2-5H3/t10-,13-,17-/m0/s1
Smiles C[C@H]1CC2=C(C(=C3[C@@H]4[C@@H](C4(C)C)CCC(=C)C3=C2C1=O)C)O
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids

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