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2-Phenylpyridine

PubChem CID: 13887

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Compound Synonyms 2-PHENYLPYRIDINE, 1008-89-5, Pyridine, 2-phenyl-, o-Phenylpyridine, 2-phenyl-pyridine, 2-(Phenyl-2-D)pyridine, EINECS 213-763-1, MFCD00006280, NSC 89291, UNII-2Y6S09838Q, NSC-89291, 2Y6S09838Q, DTXSID6074417, 372492-47-2, phenylpyridine, oPhenylpyridine, phenyl pyridine, 2-phenyl pyridine, Pyridine, 2phenyl, NSC89291, 2-Phenylpyridine, 98%, SCHEMBL35754, CHEMBL1193163, DTXCID6032560, MFCD31699954, AKOS005257841, AC-5097, CS-W007468, FP33722, AS-14490, BP-10684, SY017662, SY246291, DB-006211, NS00023005, P1039, EN300-105801, O10850, Q18205048, Z1255464971, 213-763-1
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 12.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC(C2CCCCC2)CC1
Np Classifier Class Pyridine alkaloids
Deep Smiles cccccc6))cccccn6
Heavy Atom Count 12.0
Classyfire Class Pyridines and derivatives
Description 2-phenylpyridine is a member of the class of compounds known as phenylpyridines. Phenylpyridines are polycyclic aromatic compounds containing a benzene ring linked to a pyridine ring through a CC or CN bond. 2-phenylpyridine is slightly soluble (in water) and a strong basic compound (based on its pKa). 2-phenylpyridine can be found in sweet orange and tea, which makes 2-phenylpyridine a potential biomarker for the consumption of these food products. The compound is prepared by the reaction of phenyl lithium with pyridine: C6H5Li + C5H5N → C6H5-C5H4N + LiH The reaction of iridium trichloride with 2-phenylpyridine proceeds via cyclometallation to give the chloride-bridged complex: 4 C6H5-C5H4N + 2 IrCl3(H2O)3 → Ir2Cl2(C6H4-C5H4N)4 + 4 HCl This complex can be converted to the pictured tris(cyclometallated) derivative .
Scaffold Graph Node Level C1CCC(C2CCCCN2)CC1
Classyfire Subclass Phenylpyridines
Isotope Atom Count 0.0
Molecular Complexity 127.0
Database Name fooddb_chem_all;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 2-phenylpyridine
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.6
Gsk 4 400 Rule True
Molecular Formula C11H9N
Scaffold Graph Node Bond Level c1ccc(-c2ccccn2)cc1
Inchi Key VQGHOUODWALEFC-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 1.0
Synonyms 2-Phenylpyridine, O-phenylpyridine, Pyridine, 2-phenyl-, 2-phenyl-pyridine
Esol Class Soluble
Functional Groups cnc
Compound Name 2-Phenylpyridine
Exact Mass 155.073
Formal Charge 0.0
Monoisotopic Mass 155.073
Hydrogen Bond Acceptor Count 1.0
Molecular Weight 155.2
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C11H9N/c1-2-6-10(7-3-1)11-8-4-5-9-12-11/h1-9H
Smiles C1=CC=C(C=C1)C2=CC=CC=N2
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Nicotinic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Citrus Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all