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11-Hydroxycamptothecin

PubChem CID: 135515469

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Compound Synonyms 11-Hydroxycamptothecin, 68426-53-9, (19S)-19-ethyl-6,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, DTXSID60276264, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4,8-dihydroxy-, (S)-, (19S)-19-ethyl-6,19-dihydroxy-17-oxa-3,13-diazapentacyclo(11.8.0.02,11.04,9.015,20)henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, 11-hydroxy camptothecin, CHEMBL39011, SCHEMBL935913, DTXCID30227586, AYGNHRUVJDMUQV-FQEVSTJZSA-N
Prediction Swissadme 0.0
Topological Polar Surface Area 100.0
Hydrogen Bond Donor Count 2.0
Inchi Key KXJNTORVTHBKGW-FQEVSTJZSA-N
Fcsp3 0.25
Rotatable Bond Count 1.0
Heavy Atom Count 27.0
Compound Name 11-Hydroxycamptothecin
Prediction Hob Swissadme 0.0
Exact Mass 364.106
Formal Charge 0.0
Monoisotopic Mass 364.106
Isotope Atom Count 0.0
Molecular Complexity 774.0
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 364.4
Database Name cmaup_ingredients;pubchem
Covalent Unit Count 1.0
Defined Atom Stereocenter Count 1.0
Iupac Name (19S)-19-ethyl-6,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Prediction Hob 1.0
Esol -3.9331319185185194
Inchi InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-3-4-12(23)6-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
Smiles CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C(C=CC5=C4)O)O
Xlogp 0.6
Defined Bond Stereocenter Count 0.0
Molecular Formula C20H16N2O5