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methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-4-[(2R)-5-oxopyrrolidin-2-yl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate

PubChem CID: 132599667

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Compound Synonyms NSC783580, NSC-783580
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 118.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C2CCC3CC4CCC5CCCC6CCC4(C3C2)C56)C1
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)[C@@]O)[C@H]OC=O)C)))[C@]CC))C=CCN[C@@H]6[C@@][C@H]%10NC)cc5cccc6)OC)))[C@H]CCC=O)N5)))))))))))CC5
Heavy Atom Count 39.0
Classyfire Class Plumeran-type alkaloids
Scaffold Graph Node Level OC1CCC(C2CCC3NC4CCC5CCCN6CCC4(C3C2)C56)N1
Isotope Atom Count 0.0
Molecular Complexity 1080.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-4-[(2R)-5-oxopyrrolidin-2-yl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.5
Gsk 4 400 Rule False
Molecular Formula C29H37N3O7
Scaffold Graph Node Bond Level O=C1CCC(c2ccc3c(c2)C24CCN5CC=CC(CCC2N3)C54)N1
Inchi Key BJJHBAPHTDPFRO-KSITUEMLSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 7.0
Synonyms bannucine
Esol Class Soluble
Functional Groups CC(=O)NC, CC(=O)OC, CC=CC, CN(C)C, CO, COC(C)=O, cN(C)C, cOC
Compound Name methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-4-[(2R)-5-oxopyrrolidin-2-yl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
Exact Mass 539.263
Formal Charge 0.0
Monoisotopic Mass 539.263
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 539.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C29H37N3O7/c1-6-27-10-7-12-32-13-11-28(23(27)32)18-14-17(19-8-9-22(34)30-19)21(37-4)15-20(18)31(3)24(28)29(36,26(35)38-5)25(27)39-16(2)33/h7,10,14-15,19,23-25,36H,6,8-9,11-13H2,1-5H3,(H,30,34)/t19-,23+,24-,25-,27-,28-,29+/m1/s1
Smiles CC[C@@]12C=CCN3[C@@H]1[C@]4(CC3)[C@H]([C@]([C@@H]2OC(=O)C)(C(=O)OC)O)N(C5=C4C=C(C(=C5)OC)[C@H]6CCC(=O)N6)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279