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[(1R,9R,10S,12R,13S,14R,16S,17S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] 3,4,5-trimethoxybenzoate

PubChem CID: 131881743

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 80.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1C2C3CCC4C2CC12C1CCCCC1CC2C4C3)C1CCCCC1
Np Classifier Class Corynanthe type
Deep Smiles CC[C@H][C@@H]C[C@@H]N[C@@H]6O))[C@@H][C@H]6[C@@H]OC=O)cccOC))ccc6)OC)))OC))))))))[C@][C@H]7NC)cc5cccc6))))))))C5
Heavy Atom Count 38.0
Classyfire Class Ajmaline-sarpagine alkaloids
Scaffold Graph Node Level OC(OC1C2C3CCN4C2CC12C1CCCCC1NC2C4C3)C1CCCCC1
Isotope Atom Count 0.0
Molecular Complexity 920.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name [(1R,9R,10S,12R,13S,14R,16S,17S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] 3,4,5-trimethoxybenzoate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.0
Gsk 4 400 Rule False
Molecular Formula C30H36N2O6
Scaffold Graph Node Bond Level O=C(OC1C2C3CCN4C2CC12c1ccccc1NC2C4C3)c1ccccc1
Inchi Key JCRQPLRRHXVYJF-IBICUDAGSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 7.0
Synonyms ajmalimine, ajmalimine (21-trimethoxybenzoyl ajmaline)
Esol Class Moderately soluble
Functional Groups C[C@@H](O)N(C)C, cC(=O)OC, cN(C)C, cOC
Compound Name [(1R,9R,10S,12R,13S,14R,16S,17S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] 3,4,5-trimethoxybenzoate
Exact Mass 520.257
Formal Charge 0.0
Monoisotopic Mass 520.257
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 520.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C30H36N2O6/c1-6-16-17-13-20-26-30(18-9-7-8-10-19(18)31(26)2)14-21(32(20)28(16)33)24(17)27(30)38-29(34)15-11-22(35-3)25(37-5)23(12-15)36-4/h7-12,16-17,20-21,24,26-28,33H,6,13-14H2,1-5H3/t16-,17-,20-,21-,24-,26-,27+,28+,30+/m0/s1
Smiles CC[C@H]1[C@@H]2C[C@H]3[C@H]4[C@@]5(C[C@@H]([C@H]2[C@H]5OC(=O)C6=CC(=C(C(=C6)OC)OC)OC)N3[C@@H]1O)C7=CC=CC=C7N4C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7