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methyl (1S,10S,12S,13E,18R)-13-ethylidene-18-[(3,4,5-trimethoxybenzoyl)oxymethyl]-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate

PubChem CID: 131636676

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 95.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1C2CC3C(CCC14C1CCCCC1CC34)CC2C)C1CCCCC1
Np Classifier Class Corynanthe type
Deep Smiles COC=O)[C@]COC=O)cccOC))ccc6)OC)))OC)))))))))[C@H]C[C@H]C=Ncc[C@@]95CCN9C/C/%13=C/C))))))))cccc6
Heavy Atom Count 40.0
Classyfire Class Corynanthean-type alkaloids
Scaffold Graph Node Level CC1CN2CCC34C5CCCCC5NC3C2CC1C4COC(O)C1CCCCC1
Isotope Atom Count 0.0
Molecular Complexity 1060.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (1S,10S,12S,13E,18R)-13-ethylidene-18-[(3,4,5-trimethoxybenzoyl)oxymethyl]-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.0
Gsk 4 400 Rule False
Molecular Formula C31H34N2O7
Scaffold Graph Node Bond Level C=C1CN2CCC34C(=Nc5ccccc53)C2CC1C4COC(=O)c1ccccc1
Inchi Key VFYWKVVSDATOPJ-ZETIQUPNSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 9.0
Synonyms alstolenine
Esol Class Moderately soluble
Functional Groups C/C=C(/C)C, CN(C)C, COC(C)=O, cC(=O)OC, cN=C(C)C, cOC
Compound Name methyl (1S,10S,12S,13E,18R)-13-ethylidene-18-[(3,4,5-trimethoxybenzoyl)oxymethyl]-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate
Exact Mass 546.237
Formal Charge 0.0
Monoisotopic Mass 546.237
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 546.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C31H34N2O7/c1-6-18-16-33-12-11-30-20-9-7-8-10-22(20)32-27(30)23(33)15-21(18)31(30,29(35)39-5)17-40-28(34)19-13-24(36-2)26(38-4)25(14-19)37-3/h6-10,13-14,21,23H,11-12,15-17H2,1-5H3/b18-6-/t21-,23-,30+,31-/m0/s1
Smiles C/C=C\1/CN2CC[C@@]34C5=CC=CC=C5N=C3[C@@H]2C[C@@H]1[C@@]4(COC(=O)C6=CC(=C(C(=C6)OC)OC)OC)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Reference:ISBN:9788185042114