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(R)-[(4S)-5-methyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol

PubChem CID: 129627810

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 36.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCCC2CC1CC2CCC1CC2
Deep Smiles CCCNCC[C@H]6CC6[C@@H]cccncc6cccc6))))))))))O
Heavy Atom Count 21.0
Classyfire Class Cinchona alkaloids
Scaffold Graph Node Level C1CCC2C(CC3CC4CCN3CC4)CCNC2C1
Isotope Atom Count 0.0
Molecular Complexity 374.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (R)-[(4S)-5-methyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.6
Gsk 4 400 Rule True
Molecular Formula C18H22N2O
Scaffold Graph Node Bond Level c1ccc2c(CC3CC4CCN3CC4)ccnc2c1
Inchi Key ZOZLJWFJLBUKKL-DCMVPRFGSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms cinchonidin
Esol Class Soluble
Functional Groups CN(C)C, CO, cnc
Compound Name (R)-[(4S)-5-methyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
Exact Mass 282.173
Formal Charge 0.0
Monoisotopic Mass 282.173
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 282.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C18H22N2O/c1-12-11-20-9-7-13(12)10-17(20)18(21)15-6-8-19-16-5-3-2-4-14(15)16/h2-6,8,12-13,17-18,21H,7,9-11H2,1H3/t12?,13-,17?,18+/m0/s1
Smiles CC1CN2CC[C@H]1CC2[C@@H](C3=CC=NC4=CC=CC=C34)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Cinchona Calisaya (Plant) Rel Props:Reference:ISBN:9789327275590