L-homoserine
PubChem CID: 12647
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| Compound Synonyms | L-homoserine, 672-15-1, homoserine, (2S)-2-amino-4-hydroxybutanoic acid, (s)-2-amino-4-hydroxybutanoic acid, h-hoser-oh, (S)-2-Amino-4-hydroxybutyric acid, (s)-homoserine, Homoserine (VAN), MFCD00063090, 119736-88-8, h-hse-oh, 2-Amino-4-hydroxybutyric acid, (2S)-2-ammonio-4-hydroxybutanoate, 6KA95X0IVO, Butyric acid, 2-amino-4-hydroxy-, L-, Butanoic acid, 2-amino-4-hydroxy-, (S)-, CHEBI:15699, Isothreonine, HSE, HOMOSERINE [MI], HOMOSERINE, L-, UNII-6KA95X0IVO, DTXSID5075159, L-2-Amino-4-hydroxybutyric acid, 2-amino-4-hydroxybutyrate, 2-amino-4-hydroxybutanoate, S-2-AMINO-4-HYDROXYBUTYRIC ACID, EINECS 211-590-6, NSC 206251, bmse000040, 2-amino-4-hydroxy-Butyrate, SCHEMBL29649, CHEMBL11722, 2-amino-4-hydroxy-L-Butyrate, 2-amino-4-hydroxy-Butyric acid, (S)-2-Amino-4-hydroxybutanoate, (S)-2-amino-4-hydroxy-Butanoate, 2-amino-4-hydroxy-L-Butyric acid, STR06869, s3118, (S)-2-amino-4-hydroxy-Butanoic acid, AKOS005146323, AKOS016015443, AC-5665, CS-W002292, DB04193, FH23855, HY-W002292, (S)-2-Amino-4-hydroxybutyric acid, Hse, BP-13218, L-Homoserine,labeledwith carbon-14(9ci), DB-031336, H1030, NS00079749, EN300-75344, C00263, Butyric acid, 2-amino-4-hydroxy-, L- (8CI), Q418214, Z1172369006, 09EC5004-E0F7-4325-B392-59A264DAF51F, 2-Amino-4-hydroxybutyric acid, (S)-2-Amino-4-hydroxybutanoic acid, NSC 206251 |
|---|---|
| Topological Polar Surface Area | 83.6 |
| Hydrogen Bond Donor Count | 3.0 |
| Heavy Atom Count | 8.0 |
| Description | L-homoserine, also known as 2-amino-4-hydroxybutanoic acid or isothreonine, is a member of the class of compounds known as L-alpha-amino acids. L-alpha-amino acids are alpha amino acids which have the L-configuration of the alpha-carbon atom. L-homoserine is soluble (in water) and a moderately acidic compound (based on its pKa). L-homoserine can be found in common pea, which makes L-homoserine a potential biomarker for the consumption of this food product. L-homoserine can be found primarily in blood, feces, and urine, as well as in human prostate tissue. L-homoserine exists in all living species, ranging from bacteria to humans. In humans, L-homoserine is involved in the methionine metabolism. L-homoserine is also involved in several metabolic disorders, some of which include glycine n-methyltransferase deficiency, hypermethioninemia, cystathionine beta-synthase deficiency, and methylenetetrahydrofolate reductase deficiency (MTHFRD). Homoserine (also called isothreonine) is an α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2OH. L-Homoserine is not one of the common amino acids encoded by DNA. It differs from the proteinogenic amino acid serine by insertion of an additional -CH2- unit into the backbone. Homoserine, or its lactone form, is the product of a cyanogen bromide cleavage of a peptide by degradation of methionine . |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 83.4 |
| Database Name | cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;pubchem |
| Defined Atom Stereocenter Count | 1.0 |
| Iupac Name | (2S)-2-amino-4-hydroxybutanoic acid |
| Prediction Hob | 1.0 |
| Class | Carboxylic acids and derivatives |
| Xlogp | -4.4 |
| Superclass | Organic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Molecular Formula | C4H9NO3 |
| Prediction Swissadme | 0.0 |
| Inchi Key | UKAUYVFTDYCKQA-VKHMYHEASA-N |
| Fcsp3 | 0.75 |
| Rotatable Bond Count | 3.0 |
| State | Solid |
| Synonyms | (2S)-2-Amino-4-hydroxybutanoic acid, 2-Amino-4-hydroxybutanoic acid, 2-Amino-4-hydroxybutyric acid, Homoserine, (2S)-2-Amino-4-hydroxybutanoate, 2-Amino-4-hydroxybutanoate, 2-Amino-4-hydroxybutyrate, (S)-2-Amino-4-hydroxy-butanoate, (S)-2-Amino-4-hydroxy-butanoic acid, (S)-2-Amino-4-hydroxybutanoate, (S)-2-Amino-4-hydroxybutanoic acid, (S)-Homoserine, 2-Amino-4-hydroxy-butyrate, 2-Amino-4-hydroxy-butyric acid, 2-Amino-4-hydroxy-L-butyrate, 2-Amino-4-hydroxy-L-butyric acid, Homoserine L-isomer, L Isomer OF homoserine, L-Isomer OF homoserine |
| Compound Name | L-homoserine |
| Kingdom | Organic compounds |
| Prediction Hob Swissadme | 0.0 |
| Exact Mass | 119.058 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 119.058 |
| Hydrogen Bond Acceptor Count | 4.0 |
| Molecular Weight | 119.12 |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 1.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aliphatic acyclic compounds |
| Esol | 2.378856 |
| Inchi | InChI=1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1 |
| Smiles | C(CO)[C@@H](C(=O)O)N |
| Defined Bond Stereocenter Count | 0.0 |
| Taxonomy Direct Parent | L-alpha-amino acids |
- 1. Outgoing r'ship
FOUND_INto/from Achillea Moschata (Plant) Rel Props:Source_db:cmaup_ingredients - 2. Outgoing r'ship
FOUND_INto/from Astragalus Sinicus (Plant) Rel Props:Source_db:cmaup_ingredients - 3. Outgoing r'ship
FOUND_INto/from Canavalia Gladiata (Plant) Rel Props:Source_db:cmaup_ingredients - 4. Outgoing r'ship
FOUND_INto/from Chlamydomonas Reinhardtii (Plant) Rel Props:Source_db:cmaup_ingredients - 5. Outgoing r'ship
FOUND_INto/from Eucalyptus Globulus (Plant) Rel Props:Source_db:cmaup_ingredients - 6. Outgoing r'ship
FOUND_INto/from Glycine Falcata (Plant) Rel Props:Source_db:cmaup_ingredients - 7. Outgoing r'ship
FOUND_INto/from Picradeniopsis Pringlei (Plant) Rel Props:Source_db:cmaup_ingredients - 8. Outgoing r'ship
FOUND_INto/from Pisum Sativum (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all - 9. Outgoing r'ship
FOUND_INto/from Polygonatum Cyrtonema (Plant) Rel Props:Source_db:cmaup_ingredients - 10. Outgoing r'ship
FOUND_INto/from Polygonatum Sibiricum (Plant) Rel Props:Source_db:cmaup_ingredients - 11. Outgoing r'ship
FOUND_INto/from Pterocarpus Indicus (Plant) Rel Props:Source_db:cmaup_ingredients - 12. Outgoing r'ship
FOUND_INto/from Salvia Trijuga (Plant) Rel Props:Source_db:cmaup_ingredients