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Docosanol

PubChem CID: 12620

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Compound Synonyms 1-DOCOSANOL, Docosanol, docosan-1-ol, Behenyl alcohol, 661-19-8, Behenic alcohol, Abreva, n-Docosanol, Docosyl alcohol, Lidavol, Tadenan, Stenol 1822, Lidakol, Lanette 22, Stenol 1822A, Docosanol [USAN], Nacol 22-97, IK 2, 30303-65-2, NAA 422, IK.2, NSC 8407, HSDB 5739, NSC-8407, EINECS 211-546-6, UNII-9G1OE216XY, Docosanol (Abreva), Docosanol (USAN), BRN 1770470, 9G1OE216XY, CCRIS 8943, DTXSID4027286, CHEBI:31000, AI3-36489, MFCD00002939, DTXCID907286, NSC8407, EC 211-546-6, 4-01-00-01906 (Beilstein Handbook Reference), NCGC00159370-02, DOCOSANOL (II), DOCOSANOL [II], DOCOSANOL (MART.), DOCOSANOL [MART.], Docosanol (VAN), C22H46O, Erazaban, Herepair, Healip, Cachalot BE-22, Abreva (TN), Loxiol VPG 1451, n-Docosan-1-ol, Docosanol-(1), 1-Docosanol, 98%, Cold Sore Fever Blister, DOCOSANOL [HSDB], DOCOSANOL [VANDF], N-DOCOSANOL [MI], DOCOSANOL [WHO-DD], SCHEMBL51925, DOCOSANOL [ORANGE BOOK], CHEMBL1200453, Cold Sore Fever Blister Treatment, HMS2093P22, Pharmakon1600-01505729, HY-B0222, Tox21_111611, LMFA05000008, NSC759235, s1637, AKOS015902887, CCG-213539, DB00632, NSC-759235, Behenyl alcohol, AI3-36489, Behenic alcohol, 1-Docosanol, Docosyl alcohol, IK-2, Tadenan, NCGC00159370-03, NCGC00159370-04, NCGC00159370-05, 1-Docosanol, purum, >=97.0% (GC), AC-19852, CAS-661-19-8, DA-69546, FD137295, SBI-0206938.P001, D0964, NS00009524, D03884, D70615, AB01563123_01, AB01563123_02, EN300-6495479, SR-05000001915, Q3033497, SR-05000001915-1, BRD-K50050533-001-02-1, BRD-K50050533-001-03-9, BRD-K50050533-001-04-7, A3D72D45-625E-49B5-B0FC-394010B3485D, 211-546-6, InChI=1/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 20.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Np Classifier Class Fatty alcohols
Deep Smiles CCCCCCCCCCCCCCCCCCCCCCO
Heavy Atom Count 23.0
Classyfire Class Fatty acyls
Description Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing. Docosan-1-ol is found in ginkgo nuts and potato.
Classyfire Subclass Fatty alcohols
Isotope Atom Count 0.0
Molecular Complexity 190.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q92830, n.a., O95342, P0DTD1
Iupac Name docosan-1-ol
Prediction Hob 0.0
Class Fatty Acyls
Veber Rule False
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 10.5
Superclass Lipids and lipid-like molecules
Subclass Fatty alcohols
Gsk 4 400 Rule False
Molecular Formula C22H46O
Prediction Swissadme 0.0
Inchi Key NOPFSRXAKWQILS-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 1.0
Logs -7.056
Rotatable Bond Count 20.0
State Solid
Logd 4.272
Synonyms 1-Docosanol, Abreva, Abreva (TN), Behenic alcohol, Behenyl alcohol, BEHENYL ALCOHOL, 98%, Cachalot BE-22, Debat, Dehydag wax 22 (lanette), Doconsanol, Docosanol, Docosanol (usan), Docosanol (van), Docosanol [usan], Docosanol-(1), Docosyl alcohol, Erazaban, Healip, Herepair, Lanette 22, Lidakol, Lidavol, Loxiol VPG 1451, n-Docosanol, Stenol 1822, Stenol 1822A, Tadenan, N-Docosanol, IK.2, 1-Docosonol, 1-docosanol, docosan-1-ol, docosanol, docosyl alcohol, n-1-docosanol
Substituent Name Fatty alcohol, Hydrocarbon derivative, Primary alcohol, Organooxygen compound, Alcohol, Aliphatic acyclic compound
Esol Class Poorly soluble
Functional Groups CO
Compound Name Docosanol
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 326.355
Formal Charge 0.0
Monoisotopic Mass 326.355
Hydrogen Bond Acceptor Count 1.0
Molecular Weight 326.6
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aliphatic acyclic compounds
Lipinski Rule Of 5 True
Esol -7.071775799999999
Inchi InChI=1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
Smiles CCCCCCCCCCCCCCCCCCCCCCO
Nring 0.0
Np Classifier Biosynthetic Pathway Fatty acids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent Fatty alcohols
Np Classifier Superclass Fatty acyls

  • 1. Outgoing r'ship FOUND_IN to/from Adiantum Caudatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Ammi Majus (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2009.10643749
  • 3. Outgoing r'ship FOUND_IN to/from Anacardium Occidentale (Plant) Rel Props:Reference:ISBN:9780896038776
  • 4. Outgoing r'ship FOUND_IN to/from Bergenia Purpurascens (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1689
  • 5. Outgoing r'ship FOUND_IN to/from Bergenia Stracheyi (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1689
  • 6. Outgoing r'ship FOUND_IN to/from Brunfelsia Grandiflora (Plant) Rel Props:Source_db:npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Bryum Rutilans (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Citrullus Colocynthis (Plant) Rel Props:Reference:ISBN:9788172361792
  • 9. Outgoing r'ship FOUND_IN to/from Crocus Sativus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Erythrina Variegata (Plant) Rel Props:Reference:ISBN:9788171360536; ISBN:9788172363178
  • 11. Outgoing r'ship FOUND_IN to/from Euphorbia Royleana (Plant) Rel Props:Reference:ISBN:9788185042138
  • 12. Outgoing r'ship FOUND_IN to/from Ginkgo Biloba (Plant) Rel Props:Source_db:fooddb_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Gmelina Arborea (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2009.9700165
  • 14. Outgoing r'ship FOUND_IN to/from Hedysarum Multijugum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Hibiscus Micranthus (Plant) Rel Props:Reference:ISBN:9770972795006
  • 16. Outgoing r'ship FOUND_IN to/from Mimosa Pudica (Plant) Rel Props:Reference:ISBN:9770972795006
  • 17. Outgoing r'ship FOUND_IN to/from Oenanthe Javanica (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 18. Outgoing r'ship FOUND_IN to/from Oenothera Biennis (Plant) Rel Props:Source_db:npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Phlomis Regelii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Pseudotsuga Menziesii (Plant) Rel Props:Reference:ISBN:9788172362461
  • 21. Outgoing r'ship FOUND_IN to/from Pyrus Communis (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2018.1553637
  • 22. Outgoing r'ship FOUND_IN to/from Senna Floribunda (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042114
  • 23. Outgoing r'ship FOUND_IN to/from Senna Surattensis (Plant) Rel Props:Reference:ISBN:9770972795006
  • 24. Outgoing r'ship FOUND_IN to/from Smilax Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Solanum Tuberosum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Ziziphora Clinopodioides (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2005.10643447