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14beta-Hydroxygelsedine

PubChem CID: 126023

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Compound Synonyms 14beta-Hydroxygelsedine, 14-hydroxy-gelsedine, 100482-87-9, 96681-54-8, 6-ethyl-11-hydroxy-1'-methoxyspiro[10-oxa-5-azatricyclo[5.3.1.04,8]undecane-2,3'-indole]-2'-one, Spiro(3H-indole-3,7'(6'H)-(3,6)methano(1H)oxepino(4,3-b)pyrrol)-2(1H)-one, 2'-ethyl-2',3',3'a,4',8',8'a-hexahydro-9'-hydroxy-1-methoxy-, (2'R,3S,3'S,3'aS,6'S,8'aS,9'R)-, 14-Hydroxygelsedine, 6-ethyl-11-hydroxy-1'-methoxyspiro(10-oxa-5-azatricyclo(5.3.1.04,8)undecane-2,3'-indole)-2'-one, Gelsedine, 14-hydroxy-, 14.beta.-Hydroxygelsedine, DTXSID40905545, SQDYBYDQXCTIFK-UHFFFAOYSA-N, 2'-Ethyl-9'-hydroxy-1-methoxy-2',3',3'a,4',8',8'a-hexahydro-1'H,6'H-spiro[indole-3,7'-[3,6]methanooxepino[4,3-b]pyrrol]-2(1H)-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 71.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCCCC2C12CC1CCC3CC2CCC31
Np Classifier Class Aspidosperma type
Deep Smiles CCCNCCC5CO)CCC7)cccccc6NC9=O))OC))))))))))OC6
Heavy Atom Count 25.0
Classyfire Class Gelsemium alkaloids
Scaffold Graph Node Level OC1NC2CCCCC2C12CC1NCC3CC2OCC31
Isotope Atom Count 0.0
Molecular Complexity 572.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 6-ethyl-11-hydroxy-1'-methoxyspiro[10-oxa-5-azatricyclo[5.3.1.04,8]undecane-2,3'-indole]-2'-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.9
Gsk 4 400 Rule True
Molecular Formula C19H24N2O4
Scaffold Graph Node Bond Level O=C1Nc2ccccc2C12CC1NCC3CC2OCC31
Prediction Swissadme 1.0
Inchi Key VUCHHGHARFHJBQ-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.631578947368421
Logs -2.559
Rotatable Bond Count 2.0
Logd 1.537
Synonyms 14-hydroxygelsedine, 14β-hydroxy gelsedine
Esol Class Soluble
Functional Groups CNC, CO, COC, cN(OC)C(C)=O
Compound Name 14beta-Hydroxygelsedine
Prediction Hob Swissadme 1.0
Exact Mass 344.174
Formal Charge 0.0
Monoisotopic Mass 344.174
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 344.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.6194482000000003
Inchi InChI=1S/C19H24N2O4/c1-3-12-15-10-9-25-17(16(15)22)19(8-13(10)20-12)11-6-4-5-7-14(11)21(24-2)18(19)23/h4-7,10,12-13,15-17,20,22H,3,8-9H2,1-2H3
Smiles CCC1C2C3COC(C2O)C4(CC3N1)C5=CC=CC=C5N(C4=O)OC
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Farfugium Japonicum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Gelsemium Elegans (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all