Glutathione
PubChem CID: 124886
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| Compound Synonyms | glutathione, 70-18-8, L-Glutathione, L-Glutathione reduced, Glutathion, Isethion, Tathion, Glutathione-SH, Glutinal, Tathione, reduced glutathione, Deltathione, Neuthion, Copren, Glutide, Triptide, Ledac, Glutatione, Glutatiol, GSH, Panaron, Glutathione SH, L-Glutatione, Glutathione (reduced), glutathione reduced, Agifutol S, L-Glutathione, reduced, L-gamma-glutamyl-L-cysteinylglycine, gamma-L-Glutamyl-L-cysteinylglycine, Glutathione [JAN], 5-L-Glutamyl-L-cysteinylglycine, Glutham, gamma-L-glutamyl-L-cysteinyl-glycine, Reduced l-glutathione, CCRIS 2094, gamma-L-Glutamylcysteinylglycine, glutathione red, Aec glutathione, Glycine, L-gamma-glutamyl-L-cysteinyl-, red. glutathione, Bakezyme RX, UNII-GAN16C9B8O, (S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid, EINECS 200-725-4, GAN16C9B8O, gamma-Glutamylcysteinylglycine, NSC 400639, L-Glutathione reduce, (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid, DTXSID6023101, CHEBI:16856, N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine, N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine, glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-, Glutathione (Reduced type), L-glutamyl-L-cysteinylglycine, L-Glutathione (reduced form), (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid, DTXCID903101, BenzenaMine, 2-[(4-Methoxyphenyl)Methoxy]-, 106272-20-2, 95687-20-0, GLUTATHIONE (II), GLUTATHIONE [II], MFCD00065939, GLUTATHIONE (MART.), GLUTATHIONE [MART.], GLUTATHIONE (USP-RS), GLUTATHIONE [USP-RS], [Glu(-Cys)]n-Gly, GLUTATHIONE (EP MONOGRAPH), GLUTATHIONE [EP MONOGRAPH], C10H17N3O6S, NSC400639, N5-((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)-L-glutamine, CAS-70-18-8, (S)-2-Amino-5-((R)-1-(carboxymethylamino)-3-mercapto-1-oxopropan-2-ylamino)-5-oxopentanoic acid, Glutathione, Reduced, Glutathione, l-gamma-Glutamyl-l-cysteinylglycine, SR-05000002567, Glutathione [BAN:JAN], L-gamma-glutamyl-L-cysteinyl-glycine, L-Glutathione reduced form, phytochelatins, ReadiSorb, 1lbk, NSC-400639, GSH, Glu(Cys-Gly), ?-L-Glutamyl-L-Cysteinyl-Glycine, 5-L-Glutamyl-L-cysteinylglycine, NCGC00094976-01, gamma-Glu-Cys-Gly, Tathion (TN), Glutathione (JP18), Spectrum_000419, 1oe7, 1oe8, 1r4w, C(N-.gamma.Glu-)G, GLUTATHIONE, L-, Glycine, L-.gamma.-glutamyl-L-cysteinyl-, GLUTATHIONE [MI], Reduced Glutathione,(S), Spectrum2_001500, Spectrum3_000946, Spectrum4_001056, Spectrum5_000940, ?-Glutamylcysteinylglycine, Glutathione, Reduced Form, bmse000185, bmse000952, bmse000956, GLUTATHIONE [VANDF], Cys(N-.gamma.Glu-)-Gly, SCHEMBL9167, CHEMBL1543, GLUTATHIONE [WHO-DD], KBioGR_001352, KBioSS_000899, MLS001333069, DivK1c_000075, SPECTRUM1502248, SPBio_001519, gamma-glutamyl-cysteinyl-glycine, GTPL6737, ?-L-Glutamyl-L-cysteinylglycine, L-?-glutamyl-L-cysteinylglycine, L-Glutathione reduced, 97.0%, CHEBI:60836, HMS500D17, KBio1_000075, KBio2_000899, KBio2_003467, KBio2_006035, KBio3_002012, (gamma-Glutamylcysteine)n-glycine, L-g-glutamyl-L-cysteinyl-glycine, NINDS_000075, HMS1921N22, Pharmakon1600-01502248, HARUTO HANGOVER DEFENCEPATCH, HY-D0187, L-Glutathione reduced, >=98.0%, Tox21_111371, BDBM50422268, CCG-38876, NSC758199, s4606, AKOS015999135, Tox21_111371_1, CS-7948, DB00143, FG10640, FG61468, NSC-758199, SDCCGMLS-0066687.P001, .gamma.-L-Glutamyl-L-cysteinyl-glycine, IDI1_000075, N-(N-L-?-Glutamyl-L-cysteinyl)glycine, Pharm Biol 11: 539 (1968), SMP1_000247, NCGC00264046-02, DS-14675, GSH, gamma-L-Glutamyl-L-cysteinyl-glycine, SMR000857220, SBI-0051743.P002, L-Glutathione reduced, BioXtra, >=98.0%, L-Glutathione, reduced, tested to USP spec, G0074, Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl), N-(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine, C00051, C02471, D00014, EN300-311690, P19615, AB00443568_03, Glutathione 100 microg/mL in Acetonitrile:Water, Q116907, SR-05000002567-1, SR-05000002567-2, BRD-K69346723-001-04-8, L-Glutathione reduced, Vetec(TM) reagent grade, >=98%, Z2183947556, Glutathione, European Pharmacopoeia (EP) Reference Standard, Glutathione, United States Pharmacopeia (USP) Reference Standard, Glutathione, Pharmaceutical Secondary Standard, Certified Reference Material, L-Glutathione reduced, cell culture tested, BioReagent, >=98.0%, powder, (2S)-2-AMINO-4-{[(1R)-1-[(CARBOXYMETHYL)CARBAMOYL]-2-SULFANYLETHYL]CARBAMOYLBUTANOIC ACID, 200-725-4, glutathione, l-glutathione reduced, 5-l-glutamyl-l-cysteinylglycine, gamma-l-glutamyl-l-cysteinylglycine, gsh |
|---|---|
| Ghose Rule | False |
| Classyfire Kingdom | Organic compounds |
| Topological Polar Surface Area | 160.0 |
| Hydrogen Bond Donor Count | 6.0 |
| Pfizer 3 75 Rule | True |
| Np Classifier Class | Tripeptides |
| Deep Smiles | SC[C@@H]C=O)NCC=O)O)))))NC=O)CC[C@@H]C=O)O))N |
| Heavy Atom Count | 20.0 |
| Classyfire Class | Carboxylic acids and derivatives |
| Description | Glutathione (GSH) - reduced glutathione - is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. [Wikipedia]. Glutathione is found in many foods, some of which are cashew nut, epazote, ucuhuba, and canada blueberry. |
| Classyfire Subclass | Amino acids, peptides, and analogues |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 389.0 |
| Database Name | fooddb_chem_all;hmdb_chem_all;imppat_phytochem;pubchem |
| Defined Atom Stereocenter Count | 2.0 |
| Enzyme Uniprot Id | O14684, P30041, P10768, P19440, Q9UJ14, P48637, Q16873, P28161, Q96SL4, O75715, P09488, Q9Y2Q3, O14880, P21266, P08263, O43708, P10620, Q03013, P46439, Q99735, P78417, Q7RTV2, P09210, P59796, Q16772, O15217, P07203, P36969, P22352, Q9H4Y5, P18283, P09211, O60760, P35754, Q9NS18, Q6P531, O95881, P36269, P0CG29 |
| Uniprot Id | O14684, P00390, P30041, Q04760, P10768, P19440, Q9UJ14, P48637, Q16873, P28161, Q96SL4, O75715, P09488, Q16775, Q9Y2Q3, O14880, P21266, P08263, O43708, P10620, Q03013, P46439, Q99735, P78417, Q7RTV2, P09210, P59796, Q16772, O15217, P07203, P36969, P22352, Q9H4Y5, P30711, P18283, P09211, O60760, Q92887, P35754, P33527, O15438, Q15311, O15439, O15440, Q9NS18, Q6PII5, Q6P531, O95881, A0PJJ9, P36269, Q6FII1, P0CG29, P36268, A6NGU5, Q8TED1, P0CG30, A8MPT4 |
| Iupac Name | (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid |
| Class | Carboxylic acids and derivatives |
| Veber Rule | True |
| Classyfire Superclass | Organic acids and derivatives |
| Xlogp | -4.5 |
| Superclass | Organic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Gsk 4 400 Rule | True |
| Molecular Formula | C10H17N3O6S |
| Inchi Key | RWSXRVCMGQZWBV-WDSKDSINSA-N |
| Silicos It Class | Soluble |
| Rotatable Bond Count | 9.0 |
| State | Solid |
| Synonyms | 5-L-Glutamyl-L-cysteinylglycine, Agifutol S, Bakezyme rx, Copren, Deltathione, g-L-Glutamyl-L-cysteinyl-glycine, gamma-Glutamylcysteinylglycine, gamma-L-Glutamyl-L-cysteinyl-glycine, gamma-L-Glutamyl-L-cysteinylglycine, Glutathion, Glutathione, Glutathione (reduced), Glutathione red, Glutathione reduced, Glutathione-SH, Glutathione, reduced form, Glutatiol, Glutatione, Glutide, Glutinal, GSH, Isethion, L-g-Glutamyl-L-cysteinyl-glycine, L-gamma-Glutamyl-L-cysteinyl-glycine, L-gamma-Glutamyl-L-cysteinylglycine, L-Glutamyl-L-cysteinylglycine, L-Glutathione, L-Glutathione reduce, L-Glutathione reduced, Ledac, N-(N-g-L-Glutamyl-L-cysteinyl)glycine, N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine, N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine, N-(N-γ-L-glutamyl-L-cysteinyl)glycine, Neuthion, Red. glutathione, Reduced glutathione, Tathion, Tathione, Triptide, γ-L-glutamyl-L-cysteinyl-glycine, Poly(gamma-glutamylcysteine)glycine, (gamma-Glutamylcysteine)N-glycine, Γ-L-glutamyl-L-cysteinyl-glycine, N-(N-Γ-L-glutamyl-L-cysteinyl)glycine, Poly(g-glutamylcysteine)glycine, Poly(γ-glutamylcysteine)glycine, (g-Glutamylcysteine)N-glycine, (Γ-glutamylcysteine)N-glycine, Bakezyme RX, Glutathione, reduced, gamma L Glu L cys gly, gamma-L-Glu-L-cys-gly, gamma L Glutamyl L cysteinylglycine, glutathione |
| Substituent Name | Gamma-glutamyl alpha peptide, N-acyl-aliphatic-alpha amino acid, N-acyl-alpha amino acid or derivatives, N-acyl-alpha-amino acid, Alpha-amino acid amide, L-alpha-amino acid, Alpha-amino acid or derivatives, N-substituted-alpha-amino acid, Alpha-amino acid, Amino fatty acid, Fatty acyl, Fatty acid, N-acyl-amine, Fatty amide, Dicarboxylic acid or derivatives, Secondary carboxylic acid amide, Carboxamide group, Carboxylic acid, Carboxylic acid amide, Alkylthiol, Hydrocarbon derivative, Primary amine, Organosulfur compound, Organooxygen compound, Organonitrogen compound, Primary aliphatic amine, Carbonyl group, Amine, Aliphatic acyclic compound |
| Esol Class | Highly soluble |
| Functional Groups | CC(=O)NC, CC(=O)O, CN, CNC(C)=O, CS |
| Compound Name | Glutathione |
| Kingdom | Organic compounds |
| Exact Mass | 307.084 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 307.084 |
| Hydrogen Bond Acceptor Count | 8.0 |
| Molecular Weight | 307.33 |
| Gi Absorption | False |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 2.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aliphatic acyclic compounds |
| Lipinski Rule Of 5 | True |
| Inchi | InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 |
| Smiles | C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N |
| Np Classifier Biosynthetic Pathway | Amino acids and Peptides |
| Defined Bond Stereocenter Count | 0.0 |
| Egan Rule | False |
| Taxonomy Direct Parent | Peptides |
| Np Classifier Superclass | Small peptides |
- 1. Outgoing r'ship
FOUND_INto/from Allium Cepa (Plant) Rel Props:Source_db:fooddb_chem_all - 2. Outgoing r'ship
FOUND_INto/from Allium Sativum (Plant) Rel Props:Source_db:fooddb_chem_all - 3. Outgoing r'ship
FOUND_INto/from Arachis Hypogaea (Plant) Rel Props:Source_db:fooddb_chem_all - 4. Outgoing r'ship
FOUND_INto/from Calotropis Gigantea (Plant) Rel Props:Reference:ISBN:9788172361150 - 5. Outgoing r'ship
FOUND_INto/from Capsicum Annuum (Plant) Rel Props:Reference:ISBN:9788172361150 - 6. Outgoing r'ship
FOUND_INto/from Citrus Reticulata (Plant) Rel Props:Reference:ISBN:9788172360818 - 7. Outgoing r'ship
FOUND_INto/from Cymbopogon Citratus (Plant) Rel Props:Reference:ISBN:9780387706375 - 8. Outgoing r'ship
FOUND_INto/from Ficus Benghalensis (Plant) Rel Props:Reference:ISBN:9770972795006 - 9. Outgoing r'ship
FOUND_INto/from Morus Indica (Plant) Rel Props:Reference:ISBN:9770972795006 - 10. Outgoing r'ship
FOUND_INto/from Mucuna Pruriens (Plant) Rel Props:Reference:ISBN:9788183602525 - 11. Outgoing r'ship
FOUND_INto/from Nelumbo Nucifera (Plant) Rel Props:Source_db:fooddb_chem_all - 12. Outgoing r'ship
FOUND_INto/from Phaseolus Vulgaris (Plant) Rel Props:Source_db:fooddb_chem_all - 13. Outgoing r'ship
FOUND_INto/from Portulaca Oleracea (Plant) Rel Props:Source_db:fooddb_chem_all - 14. Outgoing r'ship
FOUND_INto/from Reseda Luteola (Plant) Rel Props:Reference:ISBN:9788185042114 - 15. Outgoing r'ship
FOUND_INto/from Solanum Tuberosum (Plant) Rel Props:Source_db:fooddb_chem_all - 16. Outgoing r'ship
FOUND_INto/from Spinacia Oleracea (Plant) Rel Props:Source_db:fooddb_chem_all - 17. Outgoing r'ship
FOUND_INto/from Vicia Faba (Plant) Rel Props:Source_db:fooddb_chem_all - 18. Outgoing r'ship
FOUND_INto/from Vigna Mungo (Plant) Rel Props:Source_db:fooddb_chem_all - 19. Outgoing r'ship
FOUND_INto/from Vigna Radiata (Plant) Rel Props:Source_db:fooddb_chem_all - 20. Outgoing r'ship
FOUND_INto/from Zea Mays (Plant) Rel Props:Source_db:fooddb_chem_all