2-Pyrrolecarboxylic acid

PubChem CID: 12473

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Compound Synonyms	PYRROLE-2-CARBOXYLIC ACID, 634-97-9, 1H-Pyrrole-2-carboxylic acid, Minaline, 2-Pyrrolecarboxylic acid, Minalin, Pyrrole-2-carboxylicacid, Pyrrole-2-carboxylate, MFCD00005219, CHEBI:36751, EINECS 211-221-9, NSC 48130, NSC-48130, 2NNB85QQT9, CHEMBL509027, DTXSID50212813, 1H-Pyrrole-2-carboxylic acid (9CI), 1H-Pyrrolecarboxylic acid, PYC, Mialine, 2-Minaline, Pyrrole-2-carboxylic Acid, 2-Mialine, 2-Minaline, Minalin, Minaline, NSC 48130, Pyrrole 2-carboxylate, pyrrole, 2-carboxy-, Pyrrol-2-carboxylic acid, Pyrrole 2-carboxylic acid, 1H-pyrrole-carboxylic acid, UNII-2NNB85QQT9, SCHEMBL28298, SCHEMBL14725915, DTXCID80135304, Pyrrole-2-carboxylic acid, 99%, BCP29322, NSC48130, STR04784, BDBM50260723, s5832, STL164370, AKOS001132829, AC-6174, CS-W001963, DB02543, FG-0411, HY-W001963, PB47384, SY014890, Minaline pound>>Pyrrole-2-carboxylicacid, DB-011234, NS00014916, P1270, Pyrrole-2-carboxylic acid, Streptomyces sp., EN300-13984, C05942, AC-907/25014066, Q27104383, Z94599900, F8880-6911, 98C22043-F536-4DC6-8C61-12A0C5E6A5D6, 211-221-9
Topological Polar Surface Area	53.1
Hydrogen Bond Donor Count	2.0
Heavy Atom Count	8.0
Description	Pyrrole-2-carboxylic acid was synthesized over a century ago, but its history as a compound of biological origin is rather recent. It was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter relationship results from the lability of the direct oxidation product, A'-pyrroline-4-hydroxy-2-carboxylic acid, which loses water spontaneously to form the pyrrole. A similar reaction is catalyzed by the more specific allohydroxy-D-proline oxidase of Pseudomonas. In whole animal observations, pyrrole-2-carboxylate (PCA) ' was identified in rat or human urine after administration of the D-isomers of hydroxyproline, a finding ascribable to the action of D-amino acid oxidase. (PMID: 4430715) Urinary excretion of N-(pyrrole-2-carboxyl) glycine has been reported in a 5-year-old affected with type II hyperprolinemia, The child has mild developmental delay, recurrent seizures of the grand mal type and EEG alterations. The urinary excretion of the conjugate is stressed, since it appears that only one previous report in the literature described this compound in the urine of two patients affected by this disturbance. (PMID 2383933) [HMDB]
Isotope Atom Count	0.0
Molecular Complexity	103.0
Database Name	cmaup_ingredients;fooddb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count	0.0
Uniprot Id	P14920, P22894, P29477, P14780, P03956, P09917, P08253, P08254, P15917, O42713, P00371
Iupac Name	1H-pyrrole-2-carboxylic acid
Prediction Hob	1.0
Xlogp	0.8
Molecular Formula	C5H5NO2
Prediction Swissadme	0.0
Inchi Key	WRHZVMBBRYBTKZ-UHFFFAOYSA-N
Fcsp3	0.0
Logs	-1.005
Rotatable Bond Count	1.0
State	Solid
Logd	0.236
Synonyms	1H-Pyrrole-2-carboxylic acid, 1H-Pyrrole-2-carboxylic acid (9CI), 2-Minaline, 2-Pyrrolecarboxylate, 2-Pyrrolecarboxylic acid, Minalin, Minaline, PCA, PYC, Pyrrole-2-carboxylate, Pyrrole-2-carboxylic acid
Compound Name	2-Pyrrolecarboxylic acid
Prediction Hob Swissadme	0.0
Exact Mass	111.032
Formal Charge	0.0
Monoisotopic Mass	111.032
Hydrogen Bond Acceptor Count	2.0
Molecular Weight	111.1
Covalent Unit Count	1.0
Total Atom Stereocenter Count	0.0
Total Bond Stereocenter Count	0.0
Esol	-1.46082
Inchi	InChI=1S/C5H5NO2/c7-5(8)4-2-1-3-6-4/h1-3,6H,(H,7,8)
Smiles	C1=CNC(=C1)C(=O)O
Nring	1.0
Defined Bond Stereocenter Count	0.0

1. Outgoing r'ship FOUND_IN to/from Abroma Radix (Plant) Rel Props:Reference:
2. Outgoing r'ship FOUND_IN to/from Alstonia Yunnanensis (Plant) Rel Props:Reference:
3. Outgoing r'ship FOUND_IN to/from Amentotaxus Yunnanensis (Plant) Rel Props:Reference:
4. Outgoing r'ship FOUND_IN to/from Aristolochia Heterophylla (Plant) Rel Props:Reference:
5. Outgoing r'ship FOUND_IN to/from Atista Radix (Plant) Rel Props:Reference:
6. Outgoing r'ship FOUND_IN to/from Baliospermum Calycinum (Plant) Rel Props:Reference:
7. Outgoing r'ship FOUND_IN to/from Brachystemma Calycinum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
8. Outgoing r'ship FOUND_IN to/from Bryophyllum Calycinum (Plant) Rel Props:Reference:
9. Outgoing r'ship FOUND_IN to/from Buddleja Madagascariensis (Plant) Rel Props:Reference:
10. Outgoing r'ship FOUND_IN to/from Cabucala Madagascariensis (Plant) Rel Props:Reference:
11. Outgoing r'ship FOUND_IN to/from Cinnamosma Madagascariensis (Plant) Rel Props:Reference:
12. Outgoing r'ship FOUND_IN to/from Codonopsis Radix (Plant) Rel Props:Reference:
13. Outgoing r'ship FOUND_IN to/from Combretum Yunnanensis (Plant) Rel Props:Reference:
14. Outgoing r'ship FOUND_IN to/from Daphniphyllum Calycinum (Plant) Rel Props:Reference:
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18. Outgoing r'ship FOUND_IN to/from Ficus Heterophylla (Plant) Rel Props:Reference:
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20. Outgoing r'ship FOUND_IN to/from Girardinia Heterophylla (Plant) Rel Props:Reference:
21. Outgoing r'ship FOUND_IN to/from Givotia Moluccana (Plant) Rel Props:Reference:
22. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Yunnanensis (Plant) Rel Props:Reference:
23. Outgoing r'ship FOUND_IN to/from Hamamelis Virginiana (Plant) Rel Props:Reference:
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25. Outgoing r'ship FOUND_IN to/from Hemerocallis Radix (Plant) Rel Props:Reference:
26. Outgoing r'ship FOUND_IN to/from Hypericum Calycinum (Plant) Rel Props:Reference:
27. Outgoing r'ship FOUND_IN to/from Juniperus Ashei (Plant) Rel Props:Reference:
28. Outgoing r'ship FOUND_IN to/from Juniperus Bermudiana (Plant) Rel Props:Reference:
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30. Outgoing r'ship FOUND_IN to/from Juniperus Chinensis (Plant) Rel Props:Reference:
31. Outgoing r'ship FOUND_IN to/from Juniperus Communis (Plant) Rel Props:Reference:
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34. Outgoing r'ship FOUND_IN to/from Juniperus Formosana (Plant) Rel Props:Reference:
35. Outgoing r'ship FOUND_IN to/from Juniperus Horizontalis (Plant) Rel Props:Reference:
36. Outgoing r'ship FOUND_IN to/from Juniperus Indica (Plant) Rel Props:Reference:
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38. Outgoing r'ship FOUND_IN to/from Juniperus Occidentalis (Plant) Rel Props:Reference:
39. Outgoing r'ship FOUND_IN to/from Juniperus Oxycedrus (Plant) Rel Props:Reference:
40. Outgoing r'ship FOUND_IN to/from Juniperus Phoenicea (Plant) Rel Props:Reference:
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44. Outgoing r'ship FOUND_IN to/from Juniperus Recurva (Plant) Rel Props:Reference:
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47. Outgoing r'ship FOUND_IN to/from Juniperus Scopulorum (Plant) Rel Props:Reference:
48. Outgoing r'ship FOUND_IN to/from Juniperus Semiglobosa (Plant) Rel Props:Reference:
49. Outgoing r'ship FOUND_IN to/from Juniperus Serawschanica (Plant) Rel Props:Reference:
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51. Outgoing r'ship FOUND_IN to/from Juniperus Squamata (Plant) Rel Props:Reference:
52. Outgoing r'ship FOUND_IN to/from Juniperus Taiwaniana (Plant) Rel Props:Reference:
53. Outgoing r'ship FOUND_IN to/from Juniperus Thurifera (Plant) Rel Props:Reference:
54. Outgoing r'ship FOUND_IN to/from Juniperus Virginiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
55. Outgoing r'ship FOUND_IN to/from Lasia Heterophylla (Plant) Rel Props:Reference:
56. Outgoing r'ship FOUND_IN to/from Limnophila Heterophylla (Plant) Rel Props:Reference:
57. Outgoing r'ship FOUND_IN to/from Maytenus Heterophylla (Plant) Rel Props:Reference:
58. Outgoing r'ship FOUND_IN to/from Michelia Yunnanensis (Plant) Rel Props:Reference:
59. Outgoing r'ship FOUND_IN to/from Mimosa Abstergens (Plant) Rel Props:Reference:
60. Outgoing r'ship FOUND_IN to/from Mimosa Amara (Plant) Rel Props:Reference:
61. Outgoing r'ship FOUND_IN to/from Mimosa Diplotricha (Plant) Rel Props:Reference:
62. Outgoing r'ship FOUND_IN to/from Mimosa Elengi (Plant) Rel Props:Reference:
63. Outgoing r'ship FOUND_IN to/from Mimosa Hamata (Plant) Rel Props:Reference:
64. Outgoing r'ship FOUND_IN to/from Mimosa Invisa (Plant) Rel Props:Reference:
65. Outgoing r'ship FOUND_IN to/from Mimosa Pigra (Plant) Rel Props:Reference:
66. Outgoing r'ship FOUND_IN to/from Mimosa Pudica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
67. Outgoing r'ship FOUND_IN to/from Mimosa Rubicaulis (Plant) Rel Props:Reference:
68. Outgoing r'ship FOUND_IN to/from Mimosa Spinisilqua (Plant) Rel Props:Reference:
69. Outgoing r'ship FOUND_IN to/from Mimosa Suma (Plant) Rel Props:Reference:
70. Outgoing r'ship FOUND_IN to/from Mimosa Tenuiflora (Plant) Rel Props:Reference:
71. Outgoing r'ship FOUND_IN to/from Morus Yunnanensis (Plant) Rel Props:Reference:
72. Outgoing r'ship FOUND_IN to/from Phlegmariurus Yunnanensis (Plant) Rel Props:Reference:
73. Outgoing r'ship FOUND_IN to/from Pholidota Yunnanensis (Plant) Rel Props:Reference:
74. Outgoing r'ship FOUND_IN to/from Pinus Yunnanensis (Plant) Rel Props:Reference:
75. Outgoing r'ship FOUND_IN to/from Pleione Yunnanensis (Plant) Rel Props:Reference:
76. Outgoing r'ship FOUND_IN to/from Polygonum Virginiana (Plant) Rel Props:Reference:
77. Outgoing r'ship FOUND_IN to/from Populus Heterophylla (Plant) Rel Props:Reference:
78. Outgoing r'ship FOUND_IN to/from Populus Yunnanensis (Plant) Rel Props:Reference:
79. Outgoing r'ship FOUND_IN to/from Prunus Virginiana (Plant) Rel Props:Reference:
80. Outgoing r'ship FOUND_IN to/from Pseudostellaria Heterophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
81. Outgoing r'ship FOUND_IN to/from Psorothamnus Arborescens (Plant) Rel Props:Reference:
82. Outgoing r'ship FOUND_IN to/from Psorothamnus Junceus (Plant) Rel Props:Reference:
83. Outgoing r'ship FOUND_IN to/from Psorothamnus Polydenius (Plant) Rel Props:Reference:
84. Outgoing r'ship FOUND_IN to/from Psorothamnus Spinosus (Plant) Rel Props:Reference:
85. Outgoing r'ship FOUND_IN to/from Rauvolfia Yunnanensis (Plant) Rel Props:Reference:
86. Outgoing r'ship FOUND_IN to/from Ravenala Madagascariensis (Plant) Rel Props:Reference:
87. Outgoing r'ship FOUND_IN to/from Rohdea Japonica (Plant) Rel Props:Reference:
88. Outgoing r'ship FOUND_IN to/from Rohdea Nepalensis (Plant) Rel Props:Reference:
89. Outgoing r'ship FOUND_IN to/from Rohdea Wattii (Plant) Rel Props:Reference:
90. Outgoing r'ship FOUND_IN to/from Rubia Yunnanensis (Plant) Rel Props:Reference:
91. Outgoing r'ship FOUND_IN to/from Salacia Madagascariensis (Plant) Rel Props:Reference:
92. Outgoing r'ship FOUND_IN to/from Salvia Yunnanensis (Plant) Rel Props:Reference:
93. Outgoing r'ship FOUND_IN to/from Samadera Madagascariensis (Plant) Rel Props:Reference:
94. Outgoing r'ship FOUND_IN to/from Senecio Madagascariensis (Plant) Rel Props:Reference:
95. Outgoing r'ship FOUND_IN to/from Sinodielsia Yunnanensis (Plant) Rel Props:Reference:
96. Outgoing r'ship FOUND_IN to/from Solena Heterophylla (Plant) Rel Props:Reference:
97. Outgoing r'ship FOUND_IN to/from Swartzia Madagascariensis (Plant) Rel Props:Reference:
98. Outgoing r'ship FOUND_IN to/from Tabebuia Heterophylla (Plant) Rel Props:Reference:
99. Outgoing r'ship FOUND_IN to/from Terminalia Brachystemma (Plant) Rel Props:Reference:
100. Outgoing r'ship FOUND_IN to/from Torreya Fargesii (Plant) Rel Props:Reference:
101. Outgoing r'ship FOUND_IN to/from Torreya Yunnanensis (Plant) Rel Props:Reference:
102. Outgoing r'ship FOUND_IN to/from Tradescantia Virginiana (Plant) Rel Props:Reference:
103. Outgoing r'ship FOUND_IN to/from Tsuga Heterophylla (Plant) Rel Props:Reference:
104. Outgoing r'ship FOUND_IN to/from Walsura Yunnanensis (Plant) Rel Props:Reference:

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2-Pyrrolecarboxylic acid

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Phytochemical Properties

Associated Connections 104

Plant Connections 104