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(3beta,20alpha)-17beta-Hydroxy-9-methoxy-16beta-methoxycarbonylyohimban 4-oxide

PubChem CID: 12444713

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Compound Synonyms 1056-57-1, (3beta,20alpha)-17beta-Hydroxy-9-methoxy-16beta-methoxycarbonylyohimban 4-oxide, methyl (1R,15S,18R,19S,20S)-18-hydroxy-8-methoxy-13-oxido-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-13-ium-19-carboxylate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 89.6
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles COC=O)[C@@H][C@H]O)CC[C@H][C@@H]6C[C@@H]c[nH]ccc5CC[N+]9C%13)[O-])))))cOC))ccc6
Heavy Atom Count 29.0
Classyfire Class Yohimbine alkaloids
Scaffold Graph Node Level C1CCC2CN3CCC4C5CCCCC5NC4C3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 647.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1R,15S,18R,19S,20S)-18-hydroxy-8-methoxy-13-oxido-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-13-ium-19-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.3
Gsk 4 400 Rule False
Molecular Formula C22H28N2O5
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCCCC2C[NH+]1CC3
Inchi Key SANIGXXUGRLAGR-BXUFFXRESA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms venoxidine, venoxidine(venenatine-nb-oxide)
Esol Class Soluble
Functional Groups CO, COC(C)=O, C[N+](C)(C)[O-], cOC, c[nH]c
Compound Name (3beta,20alpha)-17beta-Hydroxy-9-methoxy-16beta-methoxycarbonylyohimban 4-oxide
Exact Mass 400.2
Formal Charge 0.0
Monoisotopic Mass 400.2
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 400.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H28N2O5/c1-28-18-5-3-4-15-19(18)13-8-9-24(27)11-12-6-7-17(25)20(22(26)29-2)14(12)10-16(24)21(13)23-15/h3-5,12,14,16-17,20,23,25H,6-11H2,1-2H3/t12-,14+,16-,17-,20+,24?/m1/s1
Smiles COC1=CC=CC2=C1C3=C(N2)[C@H]4C[C@H]5[C@H](CC[C@H]([C@H]5C(=O)OC)O)C[N+]4(CC3)[O-]
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Reference:ISBN:9788185042053; ISBN:9788185042114