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Tropigline

PubChem CID: 12444363

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Compound Synonyms tigloidin, Tropigline, Tigloidine, 495-83-0, Tiglylpseudotropine, Tropiglina, Tropiglinum, Tropintiglinat, Tigloidina, Tropyl 2,3-dimethylacrylate, Tigloyltropine, Tropigline [INN:BAN], UNII-5O258V0L5T, 5O258V0L5T, 3.beta.-Tigloyloxytropane, 3alpha-Tropanyl (E)-2-methylcrotonat, 533-08-4, 75GK1SV4EI, [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (E)-2-methylbut-2-enoate, [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (Z)-2-methylbut-2-enoate, Tigloidinum, TIGLYLTROPEINE, Tigloidine [INN:BAN], Tigloidinum [INN-Latin], Tigloidina [INN-Spanish], UNII-75GK1SV4EI, 3-tigloyloxytropane, EINECS 207-810-5, 3alpha-Tigloyloxytropane, TIGLOIDINE [MI], TIGLOIDINE [INN], TROPIGLINE [INN], Tigloyl pseudotropine, Tiglylpseudotropine, Tiglyssin, 3.alpha.-Tigloyloxytropane, TIGLOIDINE [WHO-DD], SCHEMBL932922, SCHEMBL2233976, CHEMBL2107120, CHEMBL2107196, 2-Butenoic acid, 2-methyl-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,[1a,3b(E),5a]-, UVHGSMZRSVGWDJ-LKQNJMEQSA-N, UVHGSMZRSVGWDJ-WJKWMCMVSA-N, UVHGSMZRSVGWDJ-ZCFDAEMWSA-N, DTXSID601023601, DTXSID901023824, HY-U00082, AKOS040740369, Tigloidine (3-beta-Tigloyloxytropane), CS-6695, Tropigline (3-alpha-Tigloyloxytropane), DA-78471, MS-23254, TIGLIC ACID 3.ALPHA.-TROPANYL ESTER, TIGLIC ACID ESTER WITH PSEUDOTROPINE, NS00094399, G12749, Q27262615, (E)-1.ALPHA.H,5.ALPHA.H-TROPAN-3.BETA.-OL 2-METHYLCROTONATE, (8-METHYL-8-AZABICYCLO(3.2.1)OCTAN-3-YL) (E)-2-METHYLBUT-2-ENOATE, 2-METHYL-2-BUTENOIC ACID (1.ALPHA.,3.ALPHA.(E),5.ALPHA.0- 8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, CROTONIC ACID, 2-METHYL-, 1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-YL ESTER, (E)- 3.ALPHA.
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 29.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CCC(C1)C2
Np Classifier Class Tropane alkaloids
Deep Smiles C/C=C/C=O)OCC[C@@H]CC[C@H]C7)N5C))))))))))C
Heavy Atom Count 16.0
Classyfire Class Tropane alkaloids
Scaffold Graph Node Level C1CC2CCC(C1)N2
Isotope Atom Count 0.0
Molecular Complexity 297.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (E)-2-methylbut-2-enoate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.5
Gsk 4 400 Rule True
Molecular Formula C13H21NO2
Scaffold Graph Node Bond Level C1CC2CCC(C1)N2
Inchi Key UVHGSMZRSVGWDJ-ZCFDAEMWSA-N
Silicos It Class Soluble
Rotatable Bond Count 3.0
Synonyms 3-alpha-tigloyloxytropane, 3alpha-tigloyloxytropane, 3beta-tigloyloxytropane (tigloidine), 3α-tigloyloxytropane, tigloidine
Esol Class Soluble
Functional Groups C/C=C(C)C(=O)OC, CN(C)C
Compound Name Tropigline
Exact Mass 223.157
Formal Charge 0.0
Monoisotopic Mass 223.157
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 223.31
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C13H21NO2/c1-4-9(2)13(15)16-12-7-10-5-6-11(8-12)14(10)3/h4,10-12H,5-8H2,1-3H3/b9-4+/t10-,11+,12?
Smiles C/C=C(\C)/C(=O)OC1C[C@H]2CC[C@@H](C1)N2C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

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