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2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-ylmethyl (E)-3-(4-hydroxyphenyl)prop-2-enoate

PubChem CID: 12443412

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Topological Polar Surface Area 49.8
Hydrogen Bond Donor Count 1.0
Heavy Atom Count 21.0
Description Thesinine is a member of the class of compounds known as coumaric acid esters. Coumaric acid esters are aromatic compounds containing an ester derivative of coumaric acid. Thesinine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Thesinine can be found in borage, which makes thesinine a potential biomarker for the consumption of this food product. Thesinine is a pyrrolizidine alkaloid first isolated from Thesium minkwitzianum from which it derives its name. It is also found in the flowers and seeds of borage .
Isotope Atom Count 0.0
Molecular Complexity 387.0
Database Name cmaup_ingredients;fooddb_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-ylmethyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
Nih Violation False
Prediction Hob 1.0
Xlogp 2.8
Is Pains False
Molecular Formula C17H21NO3
Prediction Swissadme 1.0
Inchi Key FQVNMXZPGWLUFZ-VMPITWQZSA-N
Fcsp3 0.4705882352941176
Rotatable Bond Count 5.0
Synonyms (-)-thesinine, Thesinine
Compound Name 2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-ylmethyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
Prediction Hob Swissadme 1.0
Exact Mass 287.152
Formal Charge 0.0
Brenk Violation True
Monoisotopic Mass 287.152
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 287.35
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 1.0
Esol -3.285954371428571
Inchi InChI=1S/C17H21NO3/c19-15-6-3-13(4-7-15)5-8-17(20)21-12-14-9-11-18-10-1-2-16(14)18/h3-8,14,16,19H,1-2,9-12H2/b8-5+
Smiles C1CC2C(CCN2C1)COC(=O)/C=C/C3=CC=C(C=C3)O
Defined Bond Stereocenter Count 1.0

  • 1. Outgoing r'ship FOUND_IN to/from Borago Officinalis (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all