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Alkaloid RP 7 from rauwolfiaperakensis

PubChem CID: 124389565

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Compound Synonyms Vinorine, 21-Deoxyvomilenine, YR8X7R4H9M, 34020-07-0, AKOS040762492, ALKALOID RP 7 FROM RAUWOLFIAPERAKENSIS, 17-O-ACETYL-.DELTA.1-1-DEMETHYLTETRAPHYLLICINE, AJMALAN-17-OL, 1,2,19,20-TETRADEHYDRO-1-DEMETHYL-, 17-ACETATE, (17R,19E)-, AJMALAN-17-OL, 1,2,19,20-TETRADEHYDRO-1-DEMETHYL-, ACETATE (ESTER), (17R,19E)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2C3CC45CC3C1CC2C4CC1CCCCC15
Np Classifier Class Corynanthe type
Deep Smiles C/C=C/CN[C@@H][C@@H][C@H]/6C[C@H]6C=Ncc[C@]5[C@@H]%10OC=O)C))))C%11))cccc6
Heavy Atom Count 25.0
Classyfire Class Ajmaline-sarpagine alkaloids
Scaffold Graph Node Level CC1CN2C3CC45CC3C1CC2C4NC1CCCCC15
Isotope Atom Count 0.0
Molecular Complexity 713.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name [(1R,10S,12R,13E,16S,17S,18R)-13-ethylidene-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6,8-tetraen-18-yl] acetate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C21H22N2O2
Scaffold Graph Node Bond Level C=C1CN2C3CC1C1CC4(CC12)C3=Nc1ccccc14
Inchi Key CLDVMRAEPFQOSD-PCTANZRLSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms vinorine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CC(=O)OC, CN(C)C, cN=C(C)C
Compound Name Alkaloid RP 7 from rauwolfiaperakensis
Exact Mass 334.168
Formal Charge 0.0
Monoisotopic Mass 334.168
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 334.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H22N2O2/c1-3-12-10-23-16-8-13(12)18-17(23)9-21(20(18)25-11(2)24)14-6-4-5-7-15(14)22-19(16)21/h3-7,13,16-18,20H,8-10H2,1-2H3/b12-3-/t13-,16-,17-,18-,20+,21+/m0/s1
Smiles C/C=C\1/CN2[C@H]3C[C@@H]1[C@H]4[C@@H]2C[C@]5([C@@H]4OC(=O)C)C3=NC6=CC=CC=C56
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7