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Methyl 18-hydroxy-6-methoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate

PubChem CID: 12314696

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 129.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1)C1CCCCC1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles COcccccc6)[nH]cc5CCNC6CCCC6)CCCC6C=O)OC))))O))OC=O)cccOC))ccc6)OC)))OC
Heavy Atom Count 43.0
Classyfire Class Yohimbine alkaloids
Scaffold Graph Node Level OC(OC1CCC2CC3C4NC5CCCCC5C4CCN3CC2C1)C1CCCCC1
Isotope Atom Count 0.0
Molecular Complexity 986.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name methyl 18-hydroxy-6-methoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.1
Gsk 4 400 Rule False
Molecular Formula C32H38N2O9
Scaffold Graph Node Bond Level O=C(OC1CCC2CC3c4[nH]c5ccccc5c4CCN3CC2C1)c1ccccc1
Inchi Key DNXIKVLOVZVMQF-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 9.0
Synonyms pseudoreserpine
Esol Class Moderately soluble
Functional Groups CN(C)C, CO, COC(C)=O, cC(=O)OC, cOC, c[nH]c
Compound Name Methyl 18-hydroxy-6-methoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Exact Mass 594.258
Formal Charge 0.0
Monoisotopic Mass 594.258
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 594.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C32H38N2O9/c1-38-18-6-7-19-20-8-9-34-15-17-12-24(43-31(36)16-10-25(39-2)30(41-4)26(11-16)40-3)29(35)27(32(37)42-5)21(17)14-23(34)28(20)33-22(19)13-18/h6-7,10-11,13,17,21,23-24,27,29,33,35H,8-9,12,14-15H2,1-5H3
Smiles COC1=CC2=C(C=C1)C3=C(N2)C4CC5C(CC(C(C5C(=O)OC)O)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC)CN4CC3
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids