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5-Hydroxy-2,2-dimethyl-6-(2-methylbutanoyl)-10-phenylpyrano[2,3-f]chromen-8-one

PubChem CID: 12314461

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 72.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC3CCCCC3C2C(C2CCCCC2)C1
Np Classifier Class Pyranocoumarins, Simple coumarins
Deep Smiles CCCC=O)ccO)cC=CCOc6cc%10oc=O)cc6cccccc6))))))))))))))C)C))))))))C
Heavy Atom Count 30.0
Classyfire Class Neoflavonoids
Scaffold Graph Node Level OC1CC(C2CCCCC2)C2C(CCC3CCCOC32)O1
Classyfire Subclass Prenylated neoflavonoids
Isotope Atom Count 0.0
Molecular Complexity 745.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-hydroxy-2,2-dimethyl-6-(2-methylbutanoyl)-10-phenylpyrano[2,3-f]chromen-8-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 5.3
Gsk 4 400 Rule False
Molecular Formula C25H24O5
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)c2c3c(ccc2o1)C=CCO3
Prediction Swissadme 1.0
Inchi Key MIXHWJJKSJFGCZ-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.28
Logs -4.128
Rotatable Bond Count 4.0
Logd 4.358
Synonyms ponnalide
Esol Class Moderately soluble
Functional Groups c=O, cC(C)=O, cC=CC, cO, cOC, coc
Compound Name 5-Hydroxy-2,2-dimethyl-6-(2-methylbutanoyl)-10-phenylpyrano[2,3-f]chromen-8-one
Prediction Hob Swissadme 1.0
Exact Mass 404.162
Formal Charge 0.0
Monoisotopic Mass 404.162
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 404.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.370031066666666
Inchi InChI=1S/C25H24O5/c1-5-14(2)21(27)20-22(28)16-11-12-25(3,4)30-23(16)19-17(13-18(26)29-24(19)20)15-9-7-6-8-10-15/h6-14,28H,5H2,1-4H3
Smiles CCC(C)C(=O)C1=C2C(=C3C(=C1O)C=CC(O3)(C)C)C(=CC(=O)O2)C4=CC=CC=C4
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Coumarins