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Picrasin B

PubChem CID: 12313355

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Compound Synonyms picrasin B, Nigakilactone I, Picrasin-B, 26121-56-2, (1S,2S,4S,6R,7S,9R,13R,17S)-4-hydroxy-15-methoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.02,7.013,17]heptadec-14-ene-3,11,16-trione, Nigakilactone I, Simalikalactone B, (1S,2S,4S,6R,7S,9R,13R,17S)-4-hydroxy-15-methoxy-2,6,14,17-tetramethyl-10-oxatetracyclo(7.7.1.02,7.013,17)heptadec-14-ene-3,11,16-trione, CHEMBL4544451, CHEBI:80890, HY-N3068, AKOS032948756, FS-9674, DA-66717, CS-0023149, C17050, Q27151386
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 89.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CCC(C)C3C4C(C)CCCC4CC(C1)C23
Np Classifier Class Quassinoids
Deep Smiles COC=CC)[C@@H]CC=O)O[C@H][C@@]6[C@H]C%10=O))[C@]C)[C@@H]C6)[C@H]C)C[C@@H]C6=O))O)))))))C
Heavy Atom Count 27.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC1CC2CCC(O)C3C4C(O)CCCC4CC(O1)C23
Classyfire Subclass Terpene lactones
Isotope Atom Count 0.0
Molecular Complexity 769.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name (1S,2S,4S,6R,7S,9R,13R,17S)-4-hydroxy-15-methoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.02,7.013,17]heptadec-14-ene-3,11,16-trione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.6
Gsk 4 400 Rule True
Molecular Formula C21H28O6
Scaffold Graph Node Bond Level O=C1CC2C=CC(=O)C3C4C(=O)CCCC4CC(O1)C23
Prediction Swissadme 1.0
Inchi Key GESOKLRVLMVNMO-WCAPFRRUSA-N
Silicos It Class Soluble
Fcsp3 0.7619047619047619
Logs -4.069
Rotatable Bond Count 1.0
Logd 1.885
Synonyms picrasin b
Esol Class Soluble
Functional Groups CC(=O)OC, CC(C)=O, CO, COC(C(C)=O)=C(C)C
Compound Name Picrasin B
Prediction Hob Swissadme 1.0
Exact Mass 376.189
Formal Charge 0.0
Monoisotopic Mass 376.189
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 376.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.122283800000001
Inchi InChI=1S/C21H28O6/c1-9-6-13(22)19(25)21(4)11(9)7-14-20(3)12(8-15(23)27-14)10(2)17(26-5)16(24)18(20)21/h9,11-14,18,22H,6-8H2,1-5H3/t9-,11+,12+,13+,14-,18+,20-,21+/m1/s1
Smiles C[C@@H]1C[C@@H](C(=O)[C@]2([C@H]1C[C@@H]3[C@@]4([C@@H]2C(=O)C(=C([C@@H]4CC(=O)O3)C)OC)C)C)O
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Triterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Picrasma Quassioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Quassia Africana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all