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Nigakilactone B

PubChem CID: 12313347

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Compound Synonyms Nigakilactone B, CHEBI:80861, Nigakilacton B, (1S,2S,6S,7S,9R,13S,14R,15S,16S,17S)-16-hydroxy-4,15-dimethoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.02,7.013,17]heptadec-4-ene-3,11-dione, CHEMBL2228444, C17013, Q27151363
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 82.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CCCC3C4C(C)CCCC4CC(C1)C23
Np Classifier Class Quassinoids
Deep Smiles CO[C@H][C@H]C)[C@@H]CC=O)O[C@H][C@@]6[C@H][C@@H]%10O))[C@]C)[C@@H]C6)[C@H]C)C=CC6=O))OC))))))))C
Heavy Atom Count 28.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC1CC2CCCC3C4C(O)CCCC4CC(O1)C23
Classyfire Subclass Terpene lactones
Isotope Atom Count 0.0
Molecular Complexity 731.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 10.0
Iupac Name (1S,2S,6S,7S,9R,13S,14R,15S,16S,17S)-16-hydroxy-4,15-dimethoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.02,7.013,17]heptadec-4-ene-3,11-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 2.5
Gsk 4 400 Rule True
Molecular Formula C22H32O6
Scaffold Graph Node Bond Level O=C1CC2CCCC3C4C(=O)C=CCC4CC(O1)C23
Prediction Swissadme 1.0
Inchi Key DCUOEDHQKMLWHI-PJZZLEGSSA-N
Silicos It Class Soluble
Fcsp3 0.8181818181818182
Logs -3.733
Rotatable Bond Count 2.0
Logd 3.155
Synonyms negakilactone-b, nigakilactone b
Esol Class Soluble
Functional Groups CC(=O)OC, CO, COC, COC(=CC)C(C)=O
Compound Name Nigakilactone B
Prediction Hob Swissadme 1.0
Exact Mass 392.22
Formal Charge 0.0
Monoisotopic Mass 392.22
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 392.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 10.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.7353504
Inchi InChI=1S/C22H32O6/c1-10-7-14(26-5)20(25)22(4)12(10)8-15-21(3)13(9-16(23)28-15)11(2)18(27-6)17(24)19(21)22/h7,10-13,15,17-19,24H,8-9H2,1-6H3/t10-,11-,12+,13+,15-,17-,18+,19+,21-,22+/m1/s1
Smiles C[C@@H]1C=C(C(=O)[C@]2([C@H]1C[C@@H]3[C@@]4([C@@H]2[C@@H]([C@H]([C@@H]([C@@H]4CC(=O)O3)C)OC)O)C)C)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Triterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Ailanthus Altissima (Plant) Rel Props:Source_db:npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Picrasma Javanica (Plant) Rel Props:Reference:ISBN:9788172362461
  • 3. Outgoing r'ship FOUND_IN to/from Picrasma Quassioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Quassia Amara (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all