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Neopodophyllotoxin

PubChem CID: 12313214

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Compound Synonyms Neopodophyllotoxin
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 92.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CC1C(C1CCCCC1)C1CC3CCCC3CC21
Np Classifier Class Arylnaphthalene and aryltetralin lignans
Deep Smiles OC[C@@H][C@H]OC=O)[C@@H]5[C@@H]cc7ccOCOc5c9)))))))))cccOC))ccc6)OC)))OC
Heavy Atom Count 30.0
Classyfire Class Lignan lactones
Scaffold Graph Node Level OC1OC2CC1C(C1CCCCC1)C1CC3OCOC3CC21
Isotope Atom Count 0.0
Molecular Complexity 629.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (1R,11R,12R,15R)-15-(hydroxymethyl)-11-(3,4,5-trimethoxyphenyl)-5,7,14-trioxatetracyclo[10.2.1.02,10.04,8]pentadeca-2,4(8),9-trien-13-one
Veber Rule True
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 2.2
Gsk 4 400 Rule False
Molecular Formula C22H22O8
Scaffold Graph Node Bond Level O=C1OC2CC1C(c1ccccc1)c1cc3c(cc12)OCO3
Inchi Key IXIUIXFHMVRZSY-XVVDYKMHSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 5.0
Synonyms neopodophyllotoxin
Esol Class Soluble
Functional Groups CO, COC(C)=O, c1cOCO1, cOC
Compound Name Neopodophyllotoxin
Exact Mass 414.131
Formal Charge 0.0
Monoisotopic Mass 414.131
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 414.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(29-9-28-14)7-12(11)20-13(8-23)19(18)22(24)30-20/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
Smiles COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@@H]([C@H](C4=CC5=C(C=C24)OCO5)OC3=O)CO
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Sinopodophyllum Hexandrum (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075