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20-Epitabernemontanine

PubChem CID: 12309361

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Compound Synonyms Dregamine, 20-Epitabernemontanine, (-)-Dregamine, 2299-26-5, methyl (1S,14S,15R,18S)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate, CHEMBL5285280, CHEBI:141897, NS00083881
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCCC(C2)CC2C1CC1CCCCC12
Np Classifier Class Corynanthe type
Deep Smiles CC[C@H]CNC)[C@@H][C@H][C@H]6CC=O)ccC8)cc[nH]5)cccc6)))))))))))C=O)OC
Heavy Atom Count 26.0
Classyfire Class Vobasan alkaloids
Scaffold Graph Node Level OC1CC2CCNC(C2)CC2C3CCCCC3NC12
Isotope Atom Count 0.0
Molecular Complexity 565.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (1S,14S,15R,18S)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.3
Gsk 4 400 Rule True
Molecular Formula C21H26N2O3
Scaffold Graph Node Bond Level O=C1CC2CCNC(Cc3c1[nH]c1ccccc31)C2
Inchi Key FFVRRQMGGGTQRH-YWKPPDPDSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms dregamine
Esol Class Moderately soluble
Functional Groups CN(C)C, COC(C)=O, cC(C)=O, c[nH]c
Compound Name 20-Epitabernemontanine
Exact Mass 354.194
Formal Charge 0.0
Monoisotopic Mass 354.194
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 354.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H26N2O3/c1-4-12-11-23(2)17-9-15-13-7-5-6-8-16(13)22-20(15)18(24)10-14(12)19(17)21(25)26-3/h5-8,12,14,17,19,22H,4,9-11H2,1-3H3/t12-,14-,17-,19-/m0/s1
Smiles CC[C@H]1CN([C@H]2CC3=C(C(=O)C[C@@H]1[C@@H]2C(=O)OC)NC4=CC=CC=C34)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids