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1-[(3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl)methyl]-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-6-ol

PubChem CID: 12305739

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 54.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCCC2CC1CCC2CCC3CCCCC3C2C1
Np Classifier Class Isoquinoline alkaloids, Terpenoid tetrahydroisoquinoline alkaloids
Deep Smiles CCCCNCCccC6CC%10CCNC)CCcc6ccOC))cc6)O))))))))))))))cccc6)OC)))OC
Heavy Atom Count 35.0
Classyfire Class Emetine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCNC2CC1CCN2CCC3CCCCC3C2C1
Isotope Atom Count 0.0
Molecular Complexity 694.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 1-[(3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl)methyl]-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-6-ol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.9
Gsk 4 400 Rule False
Molecular Formula C29H40N2O4
Scaffold Graph Node Bond Level c1ccc2c(c1)CCNC2CC1CCN2CCc3ccccc3C2C1
Inchi Key DXRJQYIJXWUNSE-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 6.0
Synonyms n-methylcephaeline
Esol Class Moderately soluble
Functional Groups CN(C)C, cO, cOC
Compound Name 1-[(3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl)methyl]-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-6-ol
Exact Mass 480.299
Formal Charge 0.0
Monoisotopic Mass 480.299
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 480.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-28(34-4)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-27(33-3)26(32)13-19(22)7-9-30(24)2/h13-16,18,21,24-25,32H,6-12,17H2,1-5H3
Smiles CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=CC(=C(C=C5CCN4C)O)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids