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(13aS)-3,4,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine

PubChem CID: 12304631

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Compound Synonyms CHEMBL520783
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.2
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3C4CCCCC4C4CCCCC4C3CC2C1
Np Classifier Class Indolizidine alkaloids
Deep Smiles COcccccc6OC))))cCNCCC[C@H]5Cc9cc%13cOC))cOC))cc6
Heavy Atom Count 29.0
Classyfire Class Phenanthrenes and derivatives
Scaffold Graph Node Level C1CCC2C(C1)C1CCCCC1C1CN3CCCC3CC21
Classyfire Subclass Phenanthroindolizidines
Isotope Atom Count 0.0
Molecular Complexity 573.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Uniprot Id n.a.
Iupac Name (13aS)-3,4,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 4.7
Gsk 4 400 Rule False
Molecular Formula C24H27NO4
Scaffold Graph Node Bond Level c1ccc2c(c1)c1c(c3ccccc32)CN2CCCC2C1
Prediction Swissadme 1.0
Inchi Key ZRGRTHUWZSWRSQ-AWEZNQCLSA-N
Silicos It Class Poorly soluble
Fcsp3 0.4166666666666667
Logs -4.636
Rotatable Bond Count 4.0
Logd 3.45
Synonyms (+)-isotylocrebrine
Esol Class Moderately soluble
Functional Groups CN(C)C, cOC
Compound Name (13aS)-3,4,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine
Prediction Hob Swissadme 1.0
Exact Mass 393.194
Formal Charge 0.0
Monoisotopic Mass 393.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 393.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.352735979310346
Inchi InChI=1S/C24H27NO4/c1-26-20-8-7-15-16-10-14-6-5-9-25(14)13-19(16)17-11-21(27-2)22(28-3)12-18(17)23(15)24(20)29-4/h7-8,11-12,14H,5-6,9-10,13H2,1-4H3/t14-/m0/s1
Smiles COC1=C(C2=C(C=C1)C3=C(CN4CCC[C@H]4C3)C5=CC(=C(C=C52)OC)OC)OC
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Tylophora Hirsuta (Plant) Rel Props:Reference:ISBN:9788172363093
  • 2. Outgoing r'ship FOUND_IN to/from Tylophora Indica (Plant) Rel Props:Reference:ISBN:9788172361150
  • 3. Outgoing r'ship FOUND_IN to/from Tylophora Tanakae (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all