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Buphanisine

PubChem CID: 12302149

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Compound Synonyms Buphanisine, (-)-buphanisine, CHEMBL512945
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 30.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CC4CCC5(CCCCC45)C3CC2C1
Np Classifier Class Amarylidaceae alkaloids, Isoquinoline alkaloids
Deep Smiles CO[C@H]C=C[C@@][C@@H]C6)NCC5))Ccc6ccOCOc5c9
Heavy Atom Count 21.0
Classyfire Class Amaryllidaceae alkaloids
Scaffold Graph Node Level C1CCC23CCN(CC4CC5OCOC5CC42)C3C1
Classyfire Subclass Crinine- and haemanthamine-type amaryllidaceae alkaloids
Isotope Atom Count 0.0
Molecular Complexity 467.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Uniprot Id n.a.
Iupac Name (1S,13R,15R)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraene
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.2
Gsk 4 400 Rule True
Molecular Formula C17H19NO3
Scaffold Graph Node Bond Level C1=CC23CCN(Cc4cc5c(cc42)OCO5)C3CC1
Prediction Swissadme 1.0
Inchi Key HATSAIPBKRRCME-JCURWCKSSA-N
Silicos It Class Soluble
Fcsp3 0.5294117647058824
Logs -2.649
Rotatable Bond Count 1.0
Logd 1.622
Synonyms (-)-buphanisine
Esol Class Soluble
Functional Groups CC=CC, CN(C)C, COC, c1cOCO1
Compound Name Buphanisine
Prediction Hob Swissadme 1.0
Exact Mass 285.136
Formal Charge 0.0
Monoisotopic Mass 285.136
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 285.34
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.165755171428571
Inchi InChI=1S/C17H19NO3/c1-19-12-2-3-17-4-5-18(16(17)7-12)9-11-6-14-15(8-13(11)17)21-10-20-14/h2-3,6,8,12,16H,4-5,7,9-10H2,1H3/t12-,16+,17+/m0/s1
Smiles CO[C@@H]1C[C@@H]2[C@@]3(CCN2CC4=CC5=C(C=C43)OCO5)C=C1
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Crinum Amabile (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Neorautanenia Mitis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all