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2,5-Dimethylfuran

PubChem CID: 12266

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Compound Synonyms 2,5-DIMETHYLFURAN, 625-86-5, Furan, 2,5-dimethyl-, 2,5-Dimethylfurane, 2,5-dimethyl-furan, 2,5-Dimethyl furan, NSC 6220, CCRIS 3158, DR5HL9OJ7Y, EINECS 210-914-3, MFCD00003250, DTXSID7022093, CHEBI:89052, AI3-21212, NSC-6220, 2,5-Dimethylfuran-d6, DIMETHYLFURAN, 2,5-, DTXCID102093, FEMA NO. 4106, 2,5-DIMETHYLFURAN [MI], 2,5-DIMETHYLFURAN [FHFI], 121571-93-5, UNII-DR5HL9OJ7Y, 2,5-Dimethylfuran, 2-Methyl-5-methylfuran, NSC 6220, NSC6220, Furan, 2,5dimethyl, 2,5-DIMETYLFURAN, 2,5-Dimethylfuran, 99%, WLN: T5OJ B1 E1, 2,5-Dimethylfuran, >=99%, CHEMBL1416448, STR09233, Tox21_202472, AKOS000120051, FD22378, PS-9347, NCGC00091694-01, NCGC00260021-01, CAS-625-86-5, DB-015920, DB-302475, D0725, NS00022555, EN300-19818, F16580, 2,5-Dimethylfuran 100 microg/mL in Acetonitrile, Q209267, 2,5-Dimethylfuran 1000 microg/mL in Acetonitrile, F0001-1679, InChI=1/C6H8O/c1-5-3-4-6(2)7-5/h3-4H,1-2H, 210-914-3
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 13.1
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCC1
Np Classifier Class Furans
Deep Smiles Ccccco5)C
Heavy Atom Count 7.0
Classyfire Class Heteroaromatic compounds
Description Maillard product 2,5-Dimethylfuran has been identified as one of the components of cigar smoke with low cilatoxicity (ability to adversely affect the cilia in the respiratory tract that are responsible for removing foreign particles). Its blood concentration can be used as a biomarker for smoking., 2,5-Dimethylfuran, together with 2,5-hexanedione and 4,5-dihydroxy-2-hexanone, is one of the main metabolites of hexane in humans, which play a role in the mechanism for the neurotoxicity of hexane., A derivative of furan, 2,5-dimethylfuran is a heterocyclic compound of the formula C6H8O. While it may be abbreviated DMF, it should not be confused with dimethylformamide. Recent advances have increased its attractiveness as a biofuel.
Scaffold Graph Node Level C1CCOC1
Isotope Atom Count 0.0
Molecular Complexity 53.2
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q9NUW8, P15917, P10145, Q03181
Iupac Name 2,5-dimethylfuran
Prediction Hob 1.0
Class Heteroaromatic compounds
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT50
Xlogp 2.2
Superclass Organoheterocyclic compounds
Gsk 4 400 Rule True
Molecular Formula C6H8O
Scaffold Graph Node Bond Level c1ccoc1
Prediction Swissadme 0.0
Inchi Key GSNUFIFRDBKVIE-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.3333333333333333
Logs -1.72
Rotatable Bond Count 0.0
State Liquid
Logd 1.918
Synonyms 2,5-Dimethyl-furan, 2,5-Dimethylfurane, Furan, 2,5-dimethyl-, 2,5-dimethylfuran
Substituent Name Heteroaromatic compound, Furan, Oxacycle, Hydrocarbon derivative, Organooxygen compound, Aromatic heteromonocyclic compound
Esol Class Soluble
Functional Groups coc
Compound Name 2,5-Dimethylfuran
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 96.0575
Formal Charge 0.0
Monoisotopic Mass 96.0575
Hydrogen Bond Acceptor Count 1.0
Molecular Weight 96.13
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteromonocyclic compounds
Lipinski Rule Of 5 True
Esol -2.3757712285714288
Inchi InChI=1S/C6H8O/c1-5-3-4-6(2)7-5/h3-4H,1-2H3
Smiles CC1=CC=C(O1)C
Nring 1.0
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Heteroaromatic compounds
Np Classifier Superclass Cyclic polyketides

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