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Taxine B

PubChem CID: 121443

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Compound Synonyms Taxine B, 1361-51-9, DTXSID40276247, (10-acetyloxy-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxo-5-tricyclo[9.3.1.03,8]pentadec-11-enyl) 3-(dimethylamino)-3-phenylpropanoate, 1361-50-8, Benzenepropanoic acid, beta-(dimethylamino)-, 5-(acetyloxy)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-4-methylene-8-oxo-9,12a,13,13-tetramethyl-6,11,12-trihydroxy-6,10-methanobenzocyclodecen-3-yl ester, CHEBI:134192, (10-acetyloxy-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxo-5-tricyclo(9.3.1.03,8)pentadec-11-enyl) 3-(dimethylamino)-3-phenylpropanoate, (1R,2R,3S,5R,8S,9S,10S)-10-(Acetyloxy)-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxotricyclo(9.3.1.0,)pentadec-11-en-5-yl (3S)-3-(dimethylamino)-3-phenylpropanoic acid, (1R,2R,3S,5R,8S,9S,10S)-10-(Acetyloxy)-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxotricyclo[9.3.1.0,]pentadec-11-en-5-yl (3S)-3-(dimethylamino)-3-phenylpropanoic acid, DTXCID40227572, (2alpha,5alpha,9alpha,10beta)-10-(acetyloxy)-1,2,9-trihydroxy-13-oxotaxa-4(20),11-dien-5-yl (3R)-3-(dimethylamino)-3-phenylpropanoate, NS00094709, C19989, 831-151-8
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 134.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC3CCC(CC(C)CCC4CCCCC4)C(C)C3CC(C1)C2
Np Classifier Class Taxane diterpenoids
Deep Smiles O=CCCcccccc6))))))NC)C))))OCCCCCC6=C))CO)CO)CC=O)C=CCC%10O))OC=O)C))))C6C)C)))C)))))))C
Heavy Atom Count 42.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level CC1C(OC(O)CCC2CCCCC2)CCC2CCC3CC(O)CC(C3)CC21
Classyfire Subclass Diterpenoids
Isotope Atom Count 0.0
Molecular Complexity 1140.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (10-acetyloxy-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxo-5-tricyclo[9.3.1.03,8]pentadec-11-enyl) 3-(dimethylamino)-3-phenylpropanoate
Prediction Hob 0.0
Class Prenol lipids
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.7
Superclass Lipids and lipid-like molecules
Subclass Diterpenoids
Gsk 4 400 Rule False
Molecular Formula C33H45NO8
Scaffold Graph Node Bond Level C=C1C(OC(=O)CCc2ccccc2)CCC2CCC3=CC(=O)CC(C3)CC12
Prediction Swissadme 0.0
Inchi Key XMZFIBDTPOUHMW-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.6060606060606061
Logs -3.717
Rotatable Bond Count 8.0
Logd 1.535
Synonyms 10-(Acetyloxy)-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxotricyclo[9.3.1.0,]pentadec-11-en-5-yl 3-(dimethylamino)-3-phenylpropanoic acid, 10-(Acetyloxy)-1,2,9-trihydroxy-8,12,15,15-tetramethyl-4-methylidene-13-oxotricyclo[9.3.1.0³,⁸]pentadec-11-en-5-yl 3-(dimethylamino)-3-phenylpropanoic acid, taxine b
Esol Class Moderately soluble
Functional Groups C=C(C)C, CC(=O)C(C)=C(C)C, CN(C)C, CO, COC(C)=O
Compound Name Taxine B
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 583.315
Formal Charge 0.0
Monoisotopic Mass 583.315
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 583.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homopolycyclic compounds
Lipinski Rule Of 5 True
Esol -4.095190685714287
Inchi InChI=1S/C33H45NO8/c1-18-23(36)17-33(40)29(38)27-19(2)24(42-25(37)16-22(34(7)8)21-12-10-9-11-13-21)14-15-32(27,6)30(39)28(41-20(3)35)26(18)31(33,4)5/h9-13,22,24,27-30,38-40H,2,14-17H2,1,3-8H3
Smiles CC1=C2C(C(C3(CCC(C(=C)C3C(C(C2(C)C)(CC1=O)O)O)OC(=O)CC(C4=CC=CC=C4)N(C)C)C)O)OC(=O)C
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent Taxanes and derivatives
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Taxus Baccata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all