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Ajugapantin A

PubChem CID: 12136681

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Compound Synonyms Ajugapantin A, CHEBI:69885, [(1R,4R,4aR,5S,7R,8S,8aR)-1,5-diacetyloxy-8-[(2S)-2-acetyloxy-2-(5-oxo-2H-furan-3-yl)ethyl]-7,8-dimethylspiro[2,3,5,6,7,8a-hexahydro-1H-naphthalene-4,2'-oxirane]-4a-yl]methyl acetate, (1R,4R,4aR,5S,6R,8S,8aR)-8a-[(acetyloxy)methyl]-5-[(2S)-2-(acetyloxy)-2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl]-5,6-dimethyloctahydro-2H-spiro[naphthalene-1,2'-oxirane]-4,8-diyl diacetate, 121449-67-0, ((1R,4R,4aR,5S,7R,8S,8aR)-1,5-diacetyloxy-8-((2S)-2-acetyloxy-2-(5-oxo-2H-furan-3-yl)ethyl)-7,8-dimethylspiro(2,3,5,6,7,8a-hexahydro-1H-naphthalene-4,2'-oxirane)-4a-yl)methyl acetate, (1R,4R,4aR,5S,6R,8S,8aR)-8a-((acetyloxy)methyl)-5-((2S)-2-(acetyloxy)-2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)-5,6-dimethyloctahydro-2H-spiro(naphthalene-1,2'-oxirane)-4,8-diyl diacetate, CHEMBL522544, Q27138229
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 144.0
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(CCC2CCCC3C2CCCC32CC2)C1
Np Classifier Class Colensane and Clerodane diterpenoids
Deep Smiles CC=O)OC[C@@][C@@H]OC=O)C)))C[C@H][C@][C@H]6[C@@H]CC[C@]%10CO3)))))OC=O)C)))))C)C[C@@H]C=CC=O)OC5)))))OC=O)C))))))C
Heavy Atom Count 39.0
Classyfire Class Carboxylic acids and derivatives
Scaffold Graph Node Level OC1CC(CCC2CCCC3C2CCCC32CO2)CO1
Classyfire Subclass Pentacarboxylic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 1080.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name [(1R,4R,4aR,5S,7R,8S,8aR)-1,5-diacetyloxy-8-[(2S)-2-acetyloxy-2-(5-oxo-2H-furan-3-yl)ethyl]-7,8-dimethylspiro[2,3,5,6,7,8a-hexahydro-1H-naphthalene-4,2'-oxirane]-4a-yl]methyl acetate
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Organic acids and derivatives
Xlogp 1.6
Gsk 4 400 Rule False
Molecular Formula C28H38O11
Scaffold Graph Node Bond Level O=C1C=C(CCC2CCCC3C2CCCC32CO2)CO1
Prediction Swissadme 0.0
Inchi Key KBIJVGBQDPMKKO-BAOLRMIKSA-N
Silicos It Class Soluble
Fcsp3 0.75
Logs -3.866
Rotatable Bond Count 12.0
Logd 2.062
Synonyms ajugapantin a
Esol Class Soluble
Functional Groups CC(=O)OC, CC1=CC(=O)OC1, COC(C)=O, C[C@@]1(C)CO1
Compound Name Ajugapantin A
Prediction Hob Swissadme 0.0
Exact Mass 550.241
Formal Charge 0.0
Monoisotopic Mass 550.241
Hydrogen Bond Acceptor Count 11.0
Molecular Weight 550.6
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Esol -3.469726200000002
Inchi InChI=1S/C28H38O11/c1-15-9-23(39-19(5)32)28(14-35-16(2)29)25(21(37-17(3)30)7-8-27(28)13-36-27)26(15,6)11-22(38-18(4)31)20-10-24(33)34-12-20/h10,15,21-23,25H,7-9,11-14H2,1-6H3/t15-,21-,22+,23+,25-,26+,27+,28-/m1/s1
Smiles C[C@@H]1C[C@@H]([C@@]2([C@@H]([C@@]1(C)C[C@@H](C3=CC(=O)OC3)OC(=O)C)[C@@H](CC[C@]24CO4)OC(=O)C)COC(=O)C)OC(=O)C
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Ajuga Ciliata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Ajuga Decumbens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Ajuga Macrosperma (Plant) Rel Props:Reference:ISBN:9788185042145
  • 4. Outgoing r'ship FOUND_IN to/from Ajuga Taiwanensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all