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methyl (12aS,12bS)-2,3-dimethoxy-7-oxido-6,8,10,11,12,12b-hexahydro-5H-isoindolo[1,2-a]isoquinolin-7-ium-12a-carboxylate

PubChem CID: 12114535

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CC3CCCCC3C12
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COC=O)[C@@]CCCC=C6C[N+][C@H]9cccOC))ccc6CC%10))))OC)))))))[O-]
Heavy Atom Count 26.0
Classyfire Class Tetrahydroisoquinolines
Scaffold Graph Node Level C1CCC2C(C1)CCN1CC3CCCCC3C21
Isotope Atom Count 0.0
Molecular Complexity 607.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name methyl (12aS,12bS)-2,3-dimethoxy-7-oxido-6,8,10,11,12,12b-hexahydro-5H-isoindolo[1,2-a]isoquinolin-7-ium-12a-carboxylate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.8
Gsk 4 400 Rule True
Molecular Formula C20H25NO5
Scaffold Graph Node Bond Level C1=C2C[NH+]3CCc4ccccc4C3C2CCC1
Inchi Key LXHLCKTUQQZKAL-WZENJKSDSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms jamtine-n-oxide
Esol Class Soluble
Functional Groups CC=C(C)C, COC(C)=O, C[N+](C)(C)[O-], cOC
Compound Name methyl (12aS,12bS)-2,3-dimethoxy-7-oxido-6,8,10,11,12,12b-hexahydro-5H-isoindolo[1,2-a]isoquinolin-7-ium-12a-carboxylate
Exact Mass 359.173
Formal Charge 0.0
Monoisotopic Mass 359.173
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 359.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H25NO5/c1-24-16-10-13-7-9-21(23)12-14-6-4-5-8-20(14,19(22)26-3)18(21)15(13)11-17(16)25-2/h6,10-11,18H,4-5,7-9,12H2,1-3H3/t18-,20-,21?/m0/s1
Smiles COC1=C(C=C2[C@H]3[C@@]4(CCCC=C4C[N+]3(CCC2=C1)[O-])C(=O)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Cocculus Hirsutus (Plant) Rel Props:Reference:ISBN:9788172363130