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3,4-Dimethylbenzoic acid

PubChem CID: 12073

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Compound Synonyms 3,4-DIMETHYLBENZOIC ACID, 619-04-5, Benzoic acid, 3,4-dimethyl-, 3,4-DiMethyl-Benzoic Acid, 1-Carboxy-3,4-dimethylbenzene, o-Xylene-4-carboxylic Acid, MFCD00002524, BRN 0907267, EINECS 210-576-7, Z2TCZ088AV, UNII-Z2TCZ088AV, DTXSID5060693, CHEBI:64818, OPVAJFQBSDUNQA-UHFFFAOYSA-, 4-09-00-01803 (Beilstein Handbook Reference), 3,4-Dimethylbenzoicacid, 3,4-dimethyl benzoic acid, 3, 4 dimethyl benzoic acid, SCHEMBL310259, DTXCID2043165, 3,4-Dimethylbenzoic acid, 98%, STL169575, AKOS000120463, AC-8956, CS-W018150, DS-1853, FD54829, FS-2351, HY-W017434, NCGC00338539-01, PD158345, SY001153, D1439, NS00015549, EN300-20154, AB01331517-02, AE-562/40207816, Q27133457, F3098-0374, Z104477078, 210-576-7
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Np Classifier Class Simple phenolic acids
Deep Smiles OC=O)cccccc6)C))C
Heavy Atom Count 11.0
Classyfire Class Benzene and substituted derivatives
Description Isolated from Eryngium foetidum (culantro) Trimethylobenzene is metabolized mainly to dimethylbenzoic (DMBA) acid. Trimethylobenzene (TMB) is a common ingredient of many organic solvents used in industry. DMBA and dimethylhippuric (DMHA) acids, excreted in urine can be used as biological indicators of exposure to TMB. (PMID: 8170375 ). 3,4-Dimethylbenzoic acid is found in herbs and spices.
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Benzoic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 154.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 3,4-dimethylbenzoic acid
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 2.7
Superclass Benzenoids
Subclass Benzoic acids and derivatives
Gsk 4 400 Rule True
Molecular Formula C9H10O2
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key OPVAJFQBSDUNQA-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.2222222222222222
Logs -4.475
Rotatable Bond Count 1.0
State Solid
Logd 3.042
Synonyms 1-carboxy-3,4-dimethylbenzene, 3,4-Dimethylbenzoate, Asym.-o-xylylic acid, Benzoic acid, 3,4-dimethyl-, unsym-o-Xylylic acid, 1-Carboxy-3,4-dimethylbenzene, 3,4-dimethylbenzoic-acid
Esol Class Soluble
Functional Groups cC(=O)O
Compound Name 3,4-Dimethylbenzoic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 150.068
Formal Charge 0.0
Monoisotopic Mass 150.068
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 150.17
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -2.4002337636363635
Inchi InChI=1S/C9H10O2/c1-6-3-4-8(9(10)11)5-7(6)2/h3-5H,1-2H3,(H,10,11)
Smiles CC1=C(C=C(C=C1)C(=O)O)C
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Benzoic acids
Np Classifier Superclass Phenolic acids (C6-C1)

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  • 10. Outgoing r'ship FOUND_IN to/from Actinidia Polygama (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Actinidia Rubricaulis (Plant) Rel Props:Reference:
  • 12. Outgoing r'ship FOUND_IN to/from Eryngium Foetidum (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
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  • 20. Outgoing r'ship FOUND_IN to/from Panax Pseudo-Ginseng (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
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