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methyl (1S,9S,14E,15S,16S,19S)-14-ethylidene-2-methyl-18-oxa-2,12-diazahexacyclo[13.3.2.01,9.03,8.09,16.012,19]icosa-3,5,7-triene-16-carboxylate

PubChem CID: 119079925

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 42.0
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC34C5CCCCC5CC35CCC4C1CC25
Np Classifier Class Corynanthe type
Deep Smiles COC=O)[C@]CO[C@@][C@@]5CCN[C@H]6C[C@H]%11/C=CC))/C6))))))))cccccc6N9C
Heavy Atom Count 27.0
Classyfire Class Corynanthean-type alkaloids
Scaffold Graph Node Level CC1CN2CCC34C5CCCCC5NC35OCC4C1CC25
Isotope Atom Count 0.0
Molecular Complexity 737.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1S,9S,14E,15S,16S,19S)-14-ethylidene-2-methyl-18-oxa-2,12-diazahexacyclo[13.3.2.01,9.03,8.09,16.012,19]icosa-3,5,7-triene-16-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C22H26N2O3
Scaffold Graph Node Bond Level C=C1CN2CCC34c5ccccc5NC35OCC4C1CC25
Inchi Key HAGBWVNSVWLTKY-SOPAEJKQSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms ψ-akuammigine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CN(C)C, COC(C)=O, cN(C)[C@](C)(C)OC
Compound Name methyl (1S,9S,14E,15S,16S,19S)-14-ethylidene-2-methyl-18-oxa-2,12-diazahexacyclo[13.3.2.01,9.03,8.09,16.012,19]icosa-3,5,7-triene-16-carboxylate
Exact Mass 366.194
Formal Charge 0.0
Monoisotopic Mass 366.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 366.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H26N2O3/c1-4-14-12-24-10-9-21-15-7-5-6-8-17(15)23(2)22(21)18(24)11-16(14)20(21,13-27-22)19(25)26-3/h4-8,16,18H,9-13H2,1-3H3/b14-4-/t16-,18-,20+,21-,22+/m0/s1
Smiles C/C=C\1/CN2CC[C@@]34C5=CC=CC=C5N([C@@]36[C@@H]2C[C@@H]1[C@]4(CO6)C(=O)OC)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Scholaris (Plant) Rel Props:Reference:ISBN:9788172361150