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Raumacline

PubChem CID: 11723922

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Compound Synonyms Raumacline, (1S,12S,13S,14R,17S,18S)-17-ethyl-3-methyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraen-14-ol, (1S,12S,13S,14R,17S,18S)-17-ethyl-3-methyl-15-oxa-3,20-diazapentacyclo(10.7.1.02,10.04,9.013,18)icosa-2(10),4,6,8-tetraen-14-ol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 46.4
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CC2CC2C3CCCCC3CC12
Np Classifier Class Carboline alkaloids
Deep Smiles CC[C@@H]CO[C@H][C@H][C@H]6C[C@@H]N[C@H]6Ccc6nC)cc5cccc6))))))))))))))))O
Heavy Atom Count 24.0
Classyfire Class Macroline alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3CC4CCOCC4C(CC21)N3
Isotope Atom Count 0.0
Molecular Complexity 486.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (1S,12S,13S,14R,17S,18S)-17-ethyl-3-methyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraen-14-ol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.4
Gsk 4 400 Rule True
Molecular Formula C20H26N2O2
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCOCC2C(C3)N1
Inchi Key HJYHBSXUKUQLLJ-SPDOYUGHSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms raumacline
Esol Class Soluble
Functional Groups CNC, CO[C@H](C)O, cn(c)C
Compound Name Raumacline
Exact Mass 326.199
Formal Charge 0.0
Monoisotopic Mass 326.199
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 326.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H26N2O2/c1-3-11-10-24-20(23)18-13(11)8-16-19-14(9-15(18)21-16)12-6-4-5-7-17(12)22(19)2/h4-7,11,13,15-16,18,20-21,23H,3,8-10H2,1-2H3/t11-,13+,15+,16+,18+,20-/m1/s1
Smiles CC[C@@H]1CO[C@H]([C@H]2[C@H]1C[C@H]3C4=C(C[C@@H]2N3)C5=CC=CC=C5N4C)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7