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methyl (1S,15S,16S,18S,20S)-20-ethyl-15-hydroxy-17-oxa-3,13-diazahexacyclo[11.7.0.02,10.03,18.04,9.016,20]icosa-2(10),4,6,8-tetraene-18-carboxylate

PubChem CID: 11646359

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 63.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)C1CCC3CCC4CC5CC4C3C1C52
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)[C@@]O[C@H][C@]C5)CC))[C@H]cn7cccccc6c9CCN%13C[C@@H]%17O
Heavy Atom Count 27.0
Classyfire Class Indolonaphthyridine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)C1CCN3CCC4OC5CC4C3C1N52
Isotope Atom Count 0.0
Molecular Complexity 673.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1S,15S,16S,18S,20S)-20-ethyl-15-hydroxy-17-oxa-3,13-diazahexacyclo[11.7.0.02,10.03,18.04,9.016,20]icosa-2(10),4,6,8-tetraene-18-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C21H24N2O4
Scaffold Graph Node Bond Level c1ccc2c(c1)c1c3n2C2CC4C(CCN(CC1)C34)O2
Inchi Key HWNBUNNVNRZPQO-XEOJFFABSA-N
Silicos It Class Soluble
Rotatable Bond Count 3.0
Synonyms vincapusine
Esol Class Soluble
Functional Groups CN(C)C, CO, COC, COC(C)=O, cn(c)C
Compound Name methyl (1S,15S,16S,18S,20S)-20-ethyl-15-hydroxy-17-oxa-3,13-diazahexacyclo[11.7.0.02,10.03,18.04,9.016,20]icosa-2(10),4,6,8-tetraene-18-carboxylate
Exact Mass 368.174
Formal Charge 0.0
Monoisotopic Mass 368.174
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 368.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O4/c1-3-20-11-21(19(25)26-2)23-14-7-5-4-6-12(14)13-8-9-22(17(20)16(13)23)10-15(24)18(20)27-21/h4-7,15,17-18,24H,3,8-11H2,1-2H3/t15-,17+,18+,20-,21-/m0/s1
Smiles CC[C@]12C[C@@]3(N4C5=CC=CC=C5C6=C4[C@H]1N(CC6)C[C@@H]([C@H]2O3)O)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Pusillus (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788172360481
  • 2. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075