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Ammothamnine

PubChem CID: 114850

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Compound Synonyms Oxymatrine, 16837-52-8, Ammothamnine, Matrine N-oxide, Matrine oxide, Matrine 1beta-oxide, CHEBI:2672, 54809-74-4, MFCD00210339, (7aS,13aR,13bR,13cS)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one 4-oxide, (1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one, (1R,2R,9S,13R,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one, Sophoridine N-oxide, Oxymatrine,(S), 1212383-03-3, SMR000543093, (+)-oxymatrine, MLS001215101, MLS006011817, Oxymatrine (Matrine N-oxide), CHEMBL458337, SCHEMBL13394285, DTXSID40937482, HMS2854E03, BBL030371, BDBM50597716, s2338, STK801916, AKOS004120031, AKOS022168212, AC-6063, CCG-267091, FO32704, NCGC00346596-01, NCGC00346596-02, 1ST40311, AS-15173, NS00018296, Q15425294, rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4-oxide, rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine4-oxide
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 38.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCCC2C1CC1CCCC3CCCC2C31
Np Classifier Class Quinolizidine alkaloids
Deep Smiles O=CCCC[C@H]N6C[C@@H]CCC[N+][C@@H]6[C@@H]%10CCC6)))))[O-]
Heavy Atom Count 19.0
Classyfire Class Lupin alkaloids
Scaffold Graph Node Level OC1CCCC2C3CCCN4CCCC(CN12)C34
Classyfire Subclass Matrine alkaloids
Isotope Atom Count 0.0
Molecular Complexity 400.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id n.a., P83916, P63092
Iupac Name (1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.0
Gsk 4 400 Rule True
Molecular Formula C15H24N2O2
Scaffold Graph Node Bond Level O=C1CCCC2C3CCC[NH+]4CCCC(CN12)C34
Prediction Swissadme 0.0
Inchi Key XVPBINOPNYFXID-LHDUFFHYSA-N
Silicos It Class Soluble
Fcsp3 0.9333333333333332
Logs -0.135
Rotatable Bond Count 0.0
Logd 0.796
Synonyms matrine n-oxide, oxymatrine
Esol Class Soluble
Functional Groups CC(=O)N(C)C, C[N+](C)(C)[O-]
Compound Name Ammothamnine
Prediction Hob Swissadme 0.0
Exact Mass 264.184
Formal Charge 0.0
Monoisotopic Mass 264.184
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 264.36
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.1216877999999997
Inchi InChI=1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
Smiles C1C[C@@H]2[C@H]3CCC[N+]4([C@H]3[C@@H](CCC4)CN2C(=O)C1)[O-]
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Euchresta Horsfieldii (Plant) Rel Props:Reference:ISBN:9788172360481
  • 2. Outgoing r'ship FOUND_IN to/from Sophora Flavescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Sophora Tomentosa (Plant) Rel Props:Reference:ISBN:9788185042084
  • 4. Outgoing r'ship FOUND_IN to/from Sophora Tonkinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all