This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration. This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration.

Lochnericine

PubChem CID: 11382599

Connections displayed (default: 10).
Loading graph...

Compound Synonyms Lochnericine, (-)-Lochnericine, 72058-36-7, Lochnericine [MI], Lochnericine, (-)-, UNII-WY97J4B4AM, WY97J4B4AM, CHEBI:6510, methyl (1R,12S,13R,15S,20R)-12-ethyl-14-oxa-8,17-diazahexacyclo[10.7.1.01,9.02,7.013,15.017,20]icosa-2,4,6,9-tetraene-10-carboxylate, (5alpha,6alpha,7alpha,12beta,19alpha)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester, Aspidospermidine-3-carboxylic acid, 2,3-didehydro-6,7-epoxy-, methyl ester, (5alpha,6alpha,7alpha,12R,19alpha)-, ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3-DIDEHYDRO-6,7-EPOXY-, METHYL ESTER, (5.ALPHA.,6.ALPHA.,7.ALPHA.,12R,19.ALPHA.)-, methyl 5alpha,6alpha,7alpha,12beta,19alpha-2,3-didehydro-6,7-epoxyaspidospermidine-3-carboxylate, (5alpha,12R,19alpha)-2,3-Didehydro-6alpha,7alpha-epoxyaspidospermidine-3-carboxylic acid methyl ester, DTXSID80312234, methyl (1R,12S,13R,15S,20R)-12-ethyl-14-oxa-8,17-diazahexacyclo(10.7.1.01,9.02,7.013,15.017,20)icosa-2,4,6,9-tetraene-10-carboxylate, SCHEMBL6535297, CHEMBL2011514, DTXCID80263358, AKOS040752642, FS-9271, NS00094486, (5a,6a,7a,12b,19a)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylate methyl ester, (5a,6a,7a,12b,19a)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester, (5.ALPHA.,6.ALPHA.,7.ALPHA.,12.BETA.,19.ALPHA.)-2,3-DIDEHYDRO-6,7-EPOXYASPIDOSPERMIDINE-3-CARBOXYLIC ACID METHYL ESTER, (5alpha,6alpha,7alpha,12beta,19alpha)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylate methyl ester
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 54.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCC3C4CC4CC4CCC12C43
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)C=CNcc[C@]5[C@@H][C@@]C9)CC))[C@H]O[C@H]3CN7CC%10))))))))))cccc6
Heavy Atom Count 26.0
Classyfire Class Aspidospermatan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC3C4OC4CN4CCC12C34
Isotope Atom Count 0.0
Molecular Complexity 705.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1R,12S,13R,15S,20R)-12-ethyl-14-oxa-8,17-diazahexacyclo[10.7.1.01,9.02,7.013,15.017,20]icosa-2,4,6,9-tetraene-10-carboxylate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.5
Gsk 4 400 Rule True
Molecular Formula C21H24N2O3
Scaffold Graph Node Bond Level C1=C2Nc3ccccc3C23CCN2CC4OC4C(C1)C23
Prediction Swissadme 1.0
Inchi Key AUVZFRDLRJQTQF-KXEYLTKFSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5714285714285714
Logs -4.086
Rotatable Bond Count 3.0
Logd 2.057
Synonyms lochnericine
Esol Class Soluble
Functional Groups CN(C)C, C[C@@H]1O[C@@H]1C, cNC(C)=C(C)C(=O)OC
Compound Name Lochnericine
Prediction Hob Swissadme 1.0
Exact Mass 352.179
Formal Charge 0.0
Monoisotopic Mass 352.179
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.5917600307692314
Inchi InChI=1S/C21H24N2O3/c1-3-20-10-12(18(24)25-2)16-21(13-6-4-5-7-14(13)22-16)8-9-23(19(20)21)11-15-17(20)26-15/h4-7,15,17,19,22H,3,8-11H2,1-2H3/t15-,17-,19-,20+,21-/m0/s1
Smiles CC[C@]12CC(=C3[C@@]4([C@H]1N(CC4)C[C@H]5[C@@H]2O5)C6=CC=CC=C6N3)C(=O)OC
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Pusillus (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9780387706375; ISBN:9788172360481; ISBN:9788185042084
  • 2. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Lobelia Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all