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16-Epivellosimine

PubChem CID: 11335328

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Compound Synonyms 16-Epivellosimine, 16-epi-Vellosimine, 16-episarpagan-17-al, CHEBI:16425, (1S,12S,13S,14R,15E)-15-ethylidene-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraene-13-carbaldehyde, (1S,12S,13S,14R,15E)-15-ethylidene-3,17-diazapentacyclo(12.3.1.02,10.04,9.012,17)octadeca-2(10),4,6,8-tetraene-13-carbaldehyde, (16S,19E)-sarpagan-17-al, DTXSID401343059, 88199-28-4, Q27101896
Topological Polar Surface Area 36.1
Hydrogen Bond Donor Count 1.0
Heavy Atom Count 22.0
Description 16-epivellosimine is a member of the class of compounds known as macroline alkaloids. Macroline alkaloids are alkaloids with a structure that is based on the tetracyclic macroline skeleton. The macroline skeleton arises by scission of the C-21 to N-4 bond of the akuammilan skeleton, and mostly occurs in bisindole alkaloids. 16-epivellosimine is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). 16-epivellosimine can be found in a number of food items such as bitter gourd, red raspberry, orange bell pepper, and star anise, which makes 16-epivellosimine a potential biomarker for the consumption of these food products.
Isotope Atom Count 0.0
Molecular Complexity 516.0
Database Name cmaup_ingredients;fooddb_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (1S,12S,13S,14R,15E)-15-ethylidene-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraene-13-carbaldehyde
Prediction Hob 1.0
Xlogp 2.0
Molecular Formula C19H20N2O
Prediction Swissadme 1.0
Inchi Key MHASSCPGKAMILD-MIOJWWSHSA-N
Fcsp3 0.4210526315789473
Logs -3.721
Rotatable Bond Count 1.0
Logd 2.928
Compound Name 16-Epivellosimine
Prediction Hob Swissadme 1.0
Exact Mass 292.158
Formal Charge 0.0
Monoisotopic Mass 292.158
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 292.4
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Esol -3.136895672727273
Inchi InChI=1S/C19H20N2O/c1-2-11-9-21-17-8-14-12-5-3-4-6-16(12)20-19(14)18(21)7-13(11)15(17)10-22/h2-6,10,13,15,17-18,20H,7-9H2,1H3/b11-2-/t13-,15-,17-,18-/m0/s1
Smiles C/C=C\1/CN2[C@H]3C[C@@H]1[C@@H]([C@@H]2CC4=C3NC5=CC=CC=C45)C=O
Nring 6.0
Defined Bond Stereocenter Count 1.0