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2-(4-hydroxy-1H-indol-3-yl)acetonitrile

PubChem CID: 11263766

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Compound Synonyms 2-(4-hydroxy-1H-indol-3-yl)acetonitrile, 118573-52-7, 4-Hydroxy-1H-indole-3-acetonitrile, 1H-Indole-3-acetonitrile, 4-hydroxy-, 4-hydroxy-3-indolacetonitril, SCHEMBL22612662, 3-(Cyanomethyl)-4-hydroxyindole, DTXSID20460445, CHEBI:173467, EN300-7434905, 840-304-8
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 59.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CCCC2C1
Np Classifier Class Aminoacids
Deep Smiles N#CCcc[nH]cc5cO)ccc6
Heavy Atom Count 13.0
Classyfire Class Indoles and derivatives
Description Present in rapeseed and in cooked Brassica vegetables as a glucosinolate dec. product. Formed from 4-Hydroxyindol-3-ylmethyl glucosinolate <ht>LBB03-D</ht>. 4-Hydroxy-1H-indole-3-acetonitrile is found in brassicas.
Scaffold Graph Node Level C1CCC2NCCC2C1
Classyfire Subclass Hydroxyindoles
Isotope Atom Count 0.0
Molecular Complexity 232.0
Database Name fooddb_chem_all;hmdb_chem_all;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 2-(4-hydroxy-1H-indol-3-yl)acetonitrile
Class Indoles and derivatives
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.3
Superclass Organoheterocyclic compounds
Subclass Hydroxyindoles
Gsk 4 400 Rule True
Molecular Formula C10H8N2O
Scaffold Graph Node Bond Level c1ccc2[nH]ccc2c1
Inchi Key RWBSUCOEZMIDSA-UHFFFAOYSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms 3-(Cyanomethyl)-4-hydroxyindole, 4-Hydroxy-1H-indole-3-acetonitrile, 4-hydroxy indolacetonitrile
Esol Class Soluble
Functional Groups CC#N, cO, c[nH]c
Compound Name 2-(4-hydroxy-1H-indol-3-yl)acetonitrile
Kingdom Organic compounds
Exact Mass 172.064
Formal Charge 0.0
Monoisotopic Mass 172.064
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 172.18
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Inchi InChI=1S/C10H8N2O/c11-5-4-7-6-12-8-2-1-3-9(13)10(7)8/h1-3,6,12-13H,4H2
Smiles C1=CC2=C(C(=C1)O)C(=CN2)CC#N
Np Classifier Biosynthetic Pathway Amino acids and Peptides, Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Hydroxyindoles
Np Classifier Superclass Small peptides

  • 1. Outgoing r'ship FOUND_IN to/from Brassica Rapa (Plant) Rel Props:Reference:ISBN:9788171360536