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Uscharin

PubChem CID: 11261800

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Compound Synonyms Uscharin, Uscharine, L7XQV67FTV, 24211-81-2, UNII-L7XQV67FTV, USCHARIN [MI], CHEMBL500585, BDBM50277175, 14-Hydroxy-2,3-((6-hydroxy-9-methyl-8-oxa-1-thia-4-azaspiro(4.5)dec-3-ene-6,7-diyl)bis(oxy))-19-oxocard-20(22)-enolide (2alpha(5S,6R,7S,9R),3beta,5alpha)-, Card-20(22)-enolide, 14-hydroxy-2,3-((6-hydroxy-9-methyl-8-oxa-1-thia-4-azaspiro(4.5)dec-3-ene-6,7-diyl)bis(oxy))-19-oxo-, (2alpha(5S,6R,7S,9R),3beta,5alpha)-, Q27282814, CARD-20(22)-ENOLIDE, 14-HYDROXY-2,3-(((5S,6R,7S,9R)-6-HYDROXY-9-METHYL-8-OXA-1-THIA-4-AZASPIRO(4.5)DEC-3-ENE-6,7-DIYL)BIS(OXY))-19-OXO-, (2.ALPHA.,3.BETA.,5.ALPHA.)-, CARD-20(22)-ENOLIDE, 14-HYDROXY-2,3-((6-HYDROXY-9-METHYL-8-OXA-1-THIA-4-AZASPIRO(4.5)DEC-3-ENE-6,7-DIYL)BIS(OXY))-19-OXO-, (2.ALPHA.(5S,6R,7S,9R),3.BETA.,5.ALPHA.)-
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 149.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC(C2CCC3C2CCC2C4CC5CC6C(CCCC67CCCC7)CC5CC4CCC23)C1
Np Classifier Class Cardenolides
Deep Smiles O=C[C@]C[C@H]O[C@]O)[C@H]O[C@@H]6C[C@@H]%10CC[C@@H][C@@H]%14CC[C@][C@]6O)CC[C@@H]5C=CC=O)OC5)))))))))C))))))))))))O[C@@H]C[C@]6SCC=N5))))))C
Heavy Atom Count 41.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC(C2CCC3C2CCC2C4CC5OC6C(OCCC67NCCS7)OC5CC4CCC23)CO1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 1230.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 13.0
Uniprot Id n.a., P46531
Iupac Name (1S,3R,5S,7R,9S,10R,12R,14R,15S,18R,19R,22S,23R)-10,22-dihydroxy-7,18-dimethyl-19-(5-oxo-2H-furan-3-yl)spiro[4,6,11-trioxahexacyclo[12.11.0.03,12.05,10.015,23.018,22]pentacosane-9,2'-5H-1,3-thiazole]-14-carbaldehyde
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.4
Gsk 4 400 Rule False
Molecular Formula C31H41NO8S
Scaffold Graph Node Bond Level O=C1C=C(C2CCC3C2CCC2C4CC5OC6C(OCCC67N=CCS7)OC5CC4CCC23)CO1
Prediction Swissadme 0.0
Inchi Key DONIPVCAKBPJLH-IGACXKNBSA-N
Silicos It Class Soluble
Fcsp3 0.8387096774193549
Logs -4.356
Rotatable Bond Count 2.0
Logd 3.487
Synonyms uscharin
Esol Class Moderately soluble
Functional Groups CC1=CC(=O)OC1, CC=O, CO, O[C@@]12OCCO[C@@H]1OCC[C@@]21N=CCS1
Compound Name Uscharin
Prediction Hob Swissadme 0.0
Exact Mass 587.255
Formal Charge 0.0
Monoisotopic Mass 587.255
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 587.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 13.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.208757000000002
Inchi InChI=1S/C31H41NO8S/c1-17-13-30(32-9-10-41-30)31(36)26(38-17)39-23-12-19-3-4-22-21(28(19,16-33)14-24(23)40-31)5-7-27(2)20(6-8-29(22,27)35)18-11-25(34)37-15-18/h9,11,16-17,19-24,26,35-36H,3-8,10,12-15H2,1-2H3/t17-,19+,20-,21+,22-,23-,24-,26+,27-,28-,29+,30+,31-/m1/s1
Smiles C[C@@H]1C[C@]2([C@]3([C@@H](O1)O[C@@H]4C[C@@H]5CC[C@@H]6[C@@H]([C@]5(C[C@H]4O3)C=O)CC[C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)N=CCS2
Nring 8.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

  • 1. Outgoing r'ship FOUND_IN to/from Anemone Narcissiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Asclepias Curassavica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Calotropis Gigantea (Plant) Rel Props:Source_db:npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Calotropis Procera (Plant) Rel Props:Reference:ISBN:9788171360536; ISBN:9788172361150
  • 5. Outgoing r'ship FOUND_IN to/from Hyperbaena Columbica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Pergularia Daemia (Plant) Rel Props:Reference:ISBN:9788172361150; ISBN:9788185042053
  • 7. Outgoing r'ship FOUND_IN to/from Viburnum Grandifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all