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Protoemetinol

PubChem CID: 11162971

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Compound Synonyms Protoemetinol, CHEMBL4556326, 2-[(2R,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]ethanol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CCCCC12
Np Classifier Class Isoquinoline alkaloids
Deep Smiles OCC[C@H]C[C@@H]NC[C@@H]6CC))))CCcc6ccOC))cc6)OC
Heavy Atom Count 23.0
Classyfire Class Quinolizidines
Scaffold Graph Node Level C1CCC2C(C1)CCN1CCCCC21
Isotope Atom Count 0.0
Molecular Complexity 378.0
Database Name imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name 2-[(2R,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]ethanol
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.0
Gsk 4 400 Rule True
Molecular Formula C19H29NO3
Scaffold Graph Node Bond Level c1ccc2c(c1)CCN1CCCCC21
Inchi Key HZYOXXWBFOLHRJ-ZQIUZPCESA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 5.0
Synonyms protoemetinol
Esol Class Soluble
Functional Groups CN(C)C, CO, cOC
Compound Name Protoemetinol
Exact Mass 319.215
Formal Charge 0.0
Monoisotopic Mass 319.215
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 319.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H29NO3/c1-4-13-12-20-7-5-15-10-18(22-2)19(23-3)11-16(15)17(20)9-14(13)6-8-21/h10-11,13-14,17,21H,4-9,12H2,1-3H3/t13-,14-,17-/m0/s1
Smiles CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1CCO)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids