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(E)-N-[(3S,4R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-4-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide

PubChem CID: 11154961

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Compound Synonyms CHEMBL2368067, BDBM50421635
Topological Polar Surface Area 52.6
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 32.0
Isotope Atom Count 0.0
Molecular Complexity 801.0
Database Name cmaup_ingredients;npass_chem_all;pubchem
Defined Atom Stereocenter Count 9.0
Uniprot Id P22303
Iupac Name (E)-N-[(3S,4R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-4-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide
Prediction Hob 0.0
Target Id NPT204
Xlogp 5.2
Molecular Formula C28H46N2O2
Prediction Swissadme 0.0
Inchi Key VLFYYOVMWNJQBE-KFRXLHHWSA-N
Fcsp3 0.8214285714285714
Logs -4.122
Rotatable Bond Count 4.0
Logd 4.204
Compound Name (E)-N-[(3S,4R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-4-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide
Prediction Hob Swissadme 0.0
Exact Mass 442.356
Formal Charge 0.0
Monoisotopic Mass 442.356
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 442.7
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 1.0
Esol -5.779365600000001
Inchi InChI=1S/C28H46N2O2/c1-8-17(2)26(32)29-24-14-16-28(5)22-13-15-27(4)20(18(3)30(6)7)11-12-21(27)19(22)9-10-23(28)25(24)31/h8,10,18-22,24-25,31H,9,11-16H2,1-7H3,(H,29,32)/b17-8+/t18-,19-,20+,21-,22-,24-,25+,27+,28+/m0/s1
Smiles C/C=C(\C)/C(=O)N[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2[C@H]1O)CC[C@@H]4[C@H](C)N(C)C)C)C
Nring 4.0
Defined Bond Stereocenter Count 1.0