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Isogarcinol

PubChem CID: 11135781

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Compound Synonyms Isogarcinol, cambogin, 71117-97-0, (1S,3S,9R,11R)-7-(3,4-dihydroxybenzoyl)-4,4,10,10-tetramethyl-3,9,11-tris(3-methylbut-2-enyl)-5-oxatricyclo[7.3.1.01,6]tridec-6-ene-8,13-dione, (3S,4aS,6R,8R)-2,2,7,7-Tetramethyl-3,6,8-tris(3-methyl-2-butenyl)-10-(3,4-dihydroxybenzoyl)-3,4,6,7-tetrahydro-5H-4a,8-methano-2H-cycloocta[b]pyran-9,11(8H)-dione, CHEMBL458934, SCHEMBL14865599, KXTNVBQRLRYVCO-LPSZMIQCSA-N, DTXSID801318189, BDBM50377962, AKOS040755482, DA-74558, HY-127087, CS-0092954, E80627
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 101.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(C1CCCCC1)C1C(C)C2CCCC3(CCCCC13)C2C
Np Classifier Class Polyprenylated cyclic polyketides (Hop meroterpenoids)
Deep Smiles CC=CC[C@]C=O)C=C[C@@]C6=O))C[C@@H]CO6)C)C))CC=CC)C))))))C[C@H]C8C)C))CC=CC)C))))))))C=O)cccccc6)O))O)))))))))))C
Heavy Atom Count 44.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC(C1CCCCC1)C1C(O)C2CCCC3(CCCOC13)C2O
Classyfire Subclass Monoterpenoids
Isotope Atom Count 0.0
Molecular Complexity 1310.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id Q09472, Q92831
Iupac Name (1S,3S,9R,11R)-7-(3,4-dihydroxybenzoyl)-4,4,10,10-tetramethyl-3,9,11-tris(3-methylbut-2-enyl)-5-oxatricyclo[7.3.1.01,6]tridec-6-ene-8,13-dione
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Target Id NPT1079
Xlogp 8.9
Gsk 4 400 Rule False
Molecular Formula C38H50O6
Scaffold Graph Node Bond Level O=C(C1=C2OCCCC23CCCC(C1=O)C3=O)c1ccccc1
Prediction Swissadme 0.0
Inchi Key KXTNVBQRLRYVCO-LPSZMIQCSA-N
Silicos It Class Poorly soluble
Fcsp3 0.5526315789473685
Logs -4.163
Rotatable Bond Count 8.0
Logd 5.601
Synonyms cambogin, isogarcinol
Esol Class Poorly soluble
Functional Groups CC(C)=O, CC=C(C)C, cC(=O)C(C(C)=O)=C(C)OC, cO
Compound Name Isogarcinol
Prediction Hob Swissadme 0.0
Exact Mass 602.361
Formal Charge 0.0
Monoisotopic Mass 602.361
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 602.8
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Esol -8.757343490909093
Inchi InChI=1S/C38H50O6/c1-22(2)11-14-26-20-37-21-27(15-12-23(3)4)36(9,10)44-33(37)30(31(41)25-13-16-28(39)29(40)19-25)32(42)38(34(37)43,35(26,7)8)18-17-24(5)6/h11-13,16-17,19,26-27,39-40H,14-15,18,20-21H2,1-10H3/t26-,27+,37+,38+/m1/s1
Smiles CC(=CC[C@@H]1C[C@]23C[C@@H](C(OC2=C(C(=O)[C@@](C3=O)(C1(C)C)CC=C(C)C)C(=O)C4=CC(=C(C=C4)O)O)(C)C)CC=C(C)C)C
Nring 4.0
Np Classifier Biosynthetic Pathway Polyketides, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Meroterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Garcinia Cowa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Garcinia Dulcis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Garcinia Indica (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/25902981
  • 4. Outgoing r'ship FOUND_IN to/from Garcinia Paucinervis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Garcinia Pedunculata (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172362300; ISBN:9788185042138; ISBN:9788190595216
  • 6. Outgoing r'ship FOUND_IN to/from Garcinia Xanthochymus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all