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Talcarpine

PubChem CID: 11131571

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Compound Synonyms Talcarpine, (1S,12S,13R,16S,17S,18R)-3,16,20-trimethyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraene-17-carbaldehyde, (1S,12S,13R,16S,17S,18R)-3,16,20-trimethyl-15-oxa-3,20-diazapentacyclo(10.7.1.02,10.04,9.013,18)icosa-2(10),4,6,8-tetraene-17-carbaldehyde, CHEMBL2332140, 38990-08-8
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 34.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CC2CC2C3CCCCC3CC12
Np Classifier Class Carboline alkaloids, Corynanthe type
Deep Smiles O=C[C@@H][C@H]C)OC[C@@H][C@H]6C[C@@H]N[C@H]6Ccc6nC)cc5cccc6)))))))))))C
Heavy Atom Count 25.0
Classyfire Class Macroline alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3CC4CCOCC4C(CC21)N3
Isotope Atom Count 0.0
Molecular Complexity 540.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Uniprot Id n.a.
Iupac Name (1S,12S,13R,16S,17S,18R)-3,16,20-trimethyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraene-17-carbaldehyde
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.2
Gsk 4 400 Rule True
Molecular Formula C21H26N2O2
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCOCC2C(C3)N1
Prediction Swissadme 1.0
Inchi Key NTXSRNQQLHZNTH-YONURWJNSA-N
Silicos It Class Soluble
Fcsp3 0.5714285714285714
Logs -3.297
Rotatable Bond Count 1.0
Logd 2.97
Synonyms talcarpine
Esol Class Soluble
Functional Groups CC=O, CN(C)C, COC, cn(c)C
Compound Name Talcarpine
Prediction Hob Swissadme 1.0
Exact Mass 338.199
Formal Charge 0.0
Monoisotopic Mass 338.199
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 338.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.512196200000001
Inchi InChI=1S/C21H26N2O2/c1-12-16(10-24)14-8-20-21-15(9-19(22(20)2)17(14)11-25-12)13-6-4-5-7-18(13)23(21)3/h4-7,10,12,14,16-17,19-20H,8-9,11H2,1-3H3/t12-,14-,16+,17+,19-,20-/m0/s1
Smiles C[C@H]1[C@H]([C@@H]2C[C@H]3C4=C(C[C@@H]([C@@H]2CO1)N3C)C5=CC=CC=C5N4C)C=O
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Angustifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Alstonia Macrophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all