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5,7-Dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-1(18),2,4(8),9,13,15(19),16-heptaene

PubChem CID: 10999422

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 23.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CC4CCC5CCCC(C3CC2C1)C54
Np Classifier Class Amarylidaceae alkaloids
Deep Smiles COccO5)ccc-cccccc6nC%10)cc5)))))))))c6
Heavy Atom Count 19.0
Classyfire Class Quinolines and derivatives
Scaffold Graph Node Level C1CC2CCN3CC4CC5OCOC5CC4C(C1)C23
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 374.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-1(18),2,4(8),9,13,15(19),16-heptaene
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.1
Gsk 4 400 Rule True
Molecular Formula C16H11NO2
Scaffold Graph Node Bond Level c1cc2c3c(c1)ccn3Cc1cc3c(cc1-2)OCO3
Prediction Swissadme 0.0
Inchi Key DXWYHCCVRJSZEP-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.125
Logs -6.405
Rotatable Bond Count 0.0
Logd 3.611
Synonyms 4,5-dehydroanhydrolycorine
Esol Class Soluble
Functional Groups c1cOCO1, cn(c)C
Compound Name 5,7-Dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-1(18),2,4(8),9,13,15(19),16-heptaene
Prediction Hob Swissadme 0.0
Exact Mass 249.079
Formal Charge 0.0
Monoisotopic Mass 249.079
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 249.26
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.9289783263157894
Inchi InChI=1S/C16H11NO2/c1-2-10-4-5-17-8-11-6-14-15(19-9-18-14)7-13(11)12(3-1)16(10)17/h1-7H,8-9H2
Smiles C1C2=CC3=C(C=C2C4=CC=CC5=C4N1C=C5)OCO3
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Corynandra Viscosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Dalbergia Candenatensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Dryopteris Dilatata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Imperata Cylindrica (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 5. Outgoing r'ship FOUND_IN to/from Ligularia Altaica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all