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(13aR)-12-ethenyl-2-hydroxy-3-methoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b][2,7]naphthyridin-8-one

PubChem CID: 10853265

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CC2C3CCCCC3CCC12
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COcccCCN[C@@H]c6cc%10O))))CccC6=O))cncc6C=C
Heavy Atom Count 24.0
Classyfire Class Diazanaphthalenes
Scaffold Graph Node Level OC1C2CNCCC2CC2C3CCCCC3CCN12
Classyfire Subclass Naphthyridines
Isotope Atom Count 0.0
Molecular Complexity 511.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (13aR)-12-ethenyl-2-hydroxy-3-methoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b][2,7]naphthyridin-8-one
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.3
Gsk 4 400 Rule True
Molecular Formula C19H18N2O3
Scaffold Graph Node Bond Level O=C1c2cnccc2CC2c3ccccc3CCN12
Inchi Key JWDQRUUCHPMNSY-MRXNPFEDSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms alangimaridine
Esol Class Soluble
Functional Groups cC(=O)N(C)C, cC=C, cO, cOC, cnc
Compound Name (13aR)-12-ethenyl-2-hydroxy-3-methoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b][2,7]naphthyridin-8-one
Exact Mass 322.132
Formal Charge 0.0
Monoisotopic Mass 322.132
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 322.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H18N2O3/c1-3-11-9-20-10-15-13(11)7-16-14-8-17(22)18(24-2)6-12(14)4-5-21(16)19(15)23/h3,6,8-10,16,22H,1,4-5,7H2,2H3/t16-/m1/s1
Smiles COC1=C(C=C2[C@H]3CC4=C(C=NC=C4C=C)C(=O)N3CCC2=C1)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alangium Salviifolium (Plant) Rel Props:Reference:ISBN:9788172361150; ISBN:9788185042138