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Nostophycin

PubChem CID: 10724374

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Compound Synonyms Nostophycin, 3-[(3R,6S,9S,18R,21S,22R,25S)-6-benzyl-3-[(2R)-butan-2-yl]-21-hydroxy-22-[(2R)-2-hydroxy-5-phenylpentyl]-2,5,8,14,17,20,24-heptaoxo-1,4,7,13,16,19,23-heptazatricyclo[23.3.0.09,13]octacosan-18-yl]propanamide, Nostophycin A, 3-((3R,6S,9S,18R,21S,22R,25S)-6-benzyl-3-((2R)-butan-2-yl)-21-hydroxy-22-((2R)-2-hydroxy-5-phenylpentyl)-2,5,8,14,17,20,24-heptaoxo-1,4,7,13,16,19,23-heptazatricyclo(23.3.0.09,13)octacosan-18-yl)propanamide, 3-((3R,6S,9S,18R,21S,22R,25S)-6-Benzyl-3-((2S)-butan-2-yl)-5,8,17,20,21,24-hexahydroxy-22-((2R)-2-hydroxy-5-phenylpentyl)-2,14-dioxo-1,4,7,13,16,19,23-heptaazatricyclo(23.3.0.0,)octacosa-4,7,16,19,23-pentaen-18-yl)propanimidate, 3-((9R,12S,13R,15aS,21R,24S,26aS)-24-benzyl-21-((R)-sec-butyl)-12-hydroxy-13-((R)-2-hydroxy-5-phenylpentyl)-5,8,11,15,20,23,26-heptaoxotetracosahydro-1H,5H-dipyrrolo(2,1-c:2',1'-l)(1,4,7,10,13,16,19)heptaazacyclodocosin-9-yl)propanamide, 3-((9R,12S,13R,15aS,21R,24S,26aS)-24-benzyl-21-((R)-sec-butyl)-12-hydroxy-13-((R)-2-hydroxy-5-phenylpentyl)-5,8,11,15,20,23,26-heptaoxotetracosahydro-1H,5H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16,19]heptaazacyclodocosin-9-yl)propanamide, 3-[(3R,6S,9S,18R,21S,22R,25S)-6-Benzyl-3-[(2S)-butan-2-yl]-5,8,17,20,21,24-hexahydroxy-22-[(2R)-2-hydroxy-5-phenylpentyl]-2,14-dioxo-1,4,7,13,16,19,23-heptaazatricyclo[23.3.0.0,]octacosa-4,7,16,19,23-pentaen-18-yl]propanimidate, CHEBI:224456, DTXSID401334763, 207450-98-4
Topological Polar Surface Area 270.0
Hydrogen Bond Donor Count 8.0
Heavy Atom Count 64.0
Isotope Atom Count 0.0
Molecular Complexity 1640.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name 3-[(3R,6S,9S,18R,21S,22R,25S)-6-benzyl-3-[(2R)-butan-2-yl]-21-hydroxy-22-[(2R)-2-hydroxy-5-phenylpentyl]-2,5,8,14,17,20,24-heptaoxo-1,4,7,13,16,19,23-heptazatricyclo[23.3.0.09,13]octacosan-18-yl]propanamide
Prediction Hob 0.0
Xlogp 1.6
Molecular Formula C46H64N8O10
Prediction Swissadme 0.0
Inchi Key UQSINWJOXDSXPH-XHECVERBSA-N
Fcsp3 0.5652173913043478
Logs -2.807
Rotatable Bond Count 13.0
Logd 1.482
Compound Name Nostophycin
Prediction Hob Swissadme 0.0
Exact Mass 888.475
Formal Charge 0.0
Monoisotopic Mass 888.475
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 889.0
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Esol -7.014346799999998
Inchi InChI=1S/C46H64N8O10/c1-3-28(2)39-46(64)54-24-12-20-36(54)44(62)50-33(26-31(55)18-10-17-29-13-6-4-7-14-29)40(58)45(63)49-32(21-22-37(47)56)41(59)48-27-38(57)53-23-11-19-35(53)43(61)51-34(42(60)52-39)25-30-15-8-5-9-16-30/h4-9,13-16,28,31-36,39-40,55,58H,3,10-12,17-27H2,1-2H3,(H2,47,56)(H,48,59)(H,49,63)(H,50,62)(H,51,61)(H,52,60)/t28-,31-,32-,33-,34+,35+,36+,39-,40+/m1/s1
Smiles CC[C@@H](C)[C@@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H]([C@@H](C(=O)N[C@@H](C(=O)NCC(=O)N3CCC[C@H]3C(=O)N[C@H](C(=O)N1)CC4=CC=CC=C4)CCC(=O)N)O)C[C@@H](CCCC5=CC=CC=C5)O
Nring 5.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Ajuga Nipponensis (Plant) Rel Props:Source_db:cmaup_ingredients
  • 2. Outgoing r'ship FOUND_IN to/from Eriobotrya Deflexa (Plant) Rel Props:Source_db:cmaup_ingredients
  • 3. Outgoing r'ship FOUND_IN to/from Grevillea Robusta (Plant) Rel Props:Source_db:cmaup_ingredients
  • 4. Outgoing r'ship FOUND_IN to/from Neurolaena Lobata (Plant) Rel Props:Source_db:cmaup_ingredients