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Flavone

PubChem CID: 10680

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Compound Synonyms FLAVONE, 525-82-6, 2-Phenyl-4H-chromen-4-one, 2-Phenylchromone, 2-Phenyl-4-chromone, Asmacoril, Chromocor, 2-phenylchromen-4-one, Cromaril, 2-Phenyl-4H-1-benzopyran-4-one, 2-Phenyl-4-benzopyron, 4H-1-Benzopyran-4-one, 2-phenyl-, Phenylchromone, 2-Phenyl-chromen-4-one, Cromarile, 2-Phenyl-gamma-benzopyrone, Flavon, 2-Phenylbenzopyran-4-one, 2-Phenyl-4H-benzopyran-4-one, 2-Phenyl-.gamma.-benzopyrone, Flavone (VAN), 2-Phenyl-4H-chromen-4-on, MFCD00006825, NSC 19028, NSC-19028, CCRIS 4288, 2-phenyl-1,4-benzopyrone, EINECS 208-383-8, UNII-S2V45N7G3B, BRN 0157598, S2V45N7G3B, DTXSID2022048, CHEBI:42491, NSC19028, FLAVONE [MI], 2-phenyl-1-benzopyran-4-one, MLS002638647, CHEMBL275638, DTXCID602048, 5-17-10-00552 (Beilstein Handbook Reference), NCGC00090962-05, CAS-525-82-6, FLN, SMR000112315, Flavone, Flavone, 4hki, 2-phenyl-4H-chromone, Maybridge3_005286, bmse000945, Flavone (VAN) (8CI), CBiol_000263, SCHEMBL18879, GTPL409, MLS002177804, MLS002473400, 2-Phenylbenzo[b]pyran-4-one, BIDD:ER0515, MEGxp0_001685, 2-Phenyl-4H-chromen-4-one #, ACon1_000055, CHEBI:24043, HMS1446A06, HMS2269O06, HMS3604K19, HY-N2424, Tox21_202987, Tox21_400059, BDBM50028962, ICCB2_000263, LMPK12110097, s3967, STK164205, AKOS000603572, CCG-214679, DB07776, FF52488, IDI1_016673, NCGC00090962-01, NCGC00090962-02, NCGC00090962-03, NCGC00090962-04, NCGC00090962-06, NCGC00168837-01, NCGC00260532-01, AC-35144, AS-58464, SY012830, DB-052142, CS-0022637, F0015, NS00007856, C10043, AH-357/03404044, EN300-18246169, L001213, CU-00000000060-1, Q2742033, BRD-K86741145-001-01-5, 6CC153EB-39A6-42FC-BE96-C8BF1D585E27, 2-Phenyl-4H-1-benzopyran-4-one, 2-Phenyl-4H-chromen-4-one, 11091-19-3, 208-383-8
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 26.3
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(C2CCCCC2)CC2CCCCC12
Np Classifier Class Flavones
Deep Smiles O=cccocc6cccc6)))))))cccccc6
Heavy Atom Count 17.0
Classyfire Class Flavonoids
Description Flavones (flavus = yellow), are a class of flavonoids based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Flavones is found in many foods, some of which are dill, feijoa, pomegranate, and rosemary.
Scaffold Graph Node Level OC1CC(C2CCCCC2)OC2CCCCC12
Classyfire Subclass Flavones
Isotope Atom Count 0.0
Molecular Complexity 326.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q12791, P15144, n.a., Q9ES14, Q16445, Q05769, P25099, P30543, P0DMS8, P28647, P78527, P15207, P80457, P00533, P14061, P37059, Q54A96, P28272, Q08493, P10275, P04150, P21397, P11511, P28845, P51151, Q16637, O15118, P15428, P04637, P08684, P52270, P62158, Q9UNQ0, Q96QE3, P08183, P19793, P03372, P83916, P10828, Q03181, P08659, P00915, P00918, Q16790, O43570, O75496, P35869, Q16236, P43220, Q9R1A7, P10145, P51449, P09874, Q9H2K2, O95271, Q9NUW8, P09917, Q15118, Q16678, P27487, P09467, P99999, P04792, P19838
Iupac Name 2-phenylchromen-4-one
Prediction Hob 1.0
Class Flavonoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT218, NPT153, NPT441, NPT537, NPT93, NPT538, NPT151, NPT539, NPT109, NPT1422, NPT947, NPT233, NPT948, NPT949, NPT2562, NPT2563, NPT588, NPT1604, NPT1592
Xlogp 3.6
Superclass Phenylpropanoids and polyketides
Subclass Flavones
Gsk 4 400 Rule True
Molecular Formula C15H10O2
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)oc2ccccc12
Prediction Swissadme 0.0
Inchi Key VHBFFQKBGNRLFZ-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.0
Logs -4.864
Rotatable Bond Count 1.0
State Solid
Logd 3.105
Synonyms 2-Phenyl-4-benzopyron, 2-Phenyl-4-chromone, 2-Phenyl-4H-1-benzopyran-4-one, 2-Phenyl-4H-benzopyran-4-one, 2-Phenyl-4H-chromen-4-one, 2-Phenyl-g-benzopyrone, 2-Phenyl-gamma-benzopyrone, 2-Phenyl-γ-benzopyrone, 2-Phenylbenzopyran-4-one, 2-Phenylchromen-4-one, 2-Phenylchromone, 4H-1-Benzopyran-4-one, 2-phenyl-, Asmacoril, Chromocor, Cromaril, Flavon, Flavone, Flavone (6CI,8CI), 2-PHENYL-4H-chromen-4-one, Flavone, 14C-labeled, 2-phenylchromone, flavone
Substituent Name Flavone, Chromone, 1-benzopyran, Benzopyran, Pyranone, Benzenoid, Pyran, Monocyclic benzene moiety, Heteroaromatic compound, Oxacycle, Organoheterocyclic compound, Hydrocarbon derivative, Organooxygen compound, Aromatic heteropolycyclic compound
Esol Class Moderately soluble
Functional Groups c=O, coc
Compound Name Flavone
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 222.068
Formal Charge 0.0
Monoisotopic Mass 222.068
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 222.24
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.354077188235294
Inchi InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H
Smiles C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Flavones
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Anethum Graveolens (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Anthocleista Grandiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Arachis Hypogaea (Plant) Rel Props:Reference:ISBN:9788172363178
  • 4. Outgoing r'ship FOUND_IN to/from Asplenium Normale (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Brucea Javanica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Carpobrotus Edulis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Castanea Crenata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Centrolobium Tomentosum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Ceratophyllum Submersum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Chamaemelum Nobile (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Chrysanthemum Morifolium (Plant) Rel Props:Source_db:npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Chukrasia Tabularis (Plant) Rel Props:Reference:ISBN:9789327275590
  • 13. Outgoing r'ship FOUND_IN to/from Commelina Communis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Desmodium Styracifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Dracocephalum Kotschyi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 16. Outgoing r'ship FOUND_IN to/from Feijoa Sellowiana (Plant) Rel Props:Source_db:fooddb_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Helleborus Caucasicus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Hemerocallis Minor (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Hypericum Perforatum (Plant) Rel Props:Reference:ISBN:9780896038776
  • 20. Outgoing r'ship FOUND_IN to/from Hypoestes Serpens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 21. Outgoing r'ship FOUND_IN to/from Ilex Rotunda (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Justicia Adhatoda (Plant) Rel Props:Reference:ISBN:9770972795006
  • 23. Outgoing r'ship FOUND_IN to/from Lespedeza Homoloba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Lippia Carviodora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Lolium Perenne (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Myrica Nana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 27. Outgoing r'ship FOUND_IN to/from Oroxylum Indicum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Phoenix Dactylifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Primula Farinosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 30. Outgoing r'ship FOUND_IN to/from Primula Macrophylla (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/18686139
  • 31. Outgoing r'ship FOUND_IN to/from Primula Pulverulenta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 32. Outgoing r'ship FOUND_IN to/from Psilostrophe Cooperi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Punica Granatum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 34. Outgoing r'ship FOUND_IN to/from Rosmarinus Officinalis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 35. Outgoing r'ship FOUND_IN to/from Schkuhria Multiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 36. Outgoing r'ship FOUND_IN to/from Sideritis Tragoriganum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 37. Outgoing r'ship FOUND_IN to/from Solanum Jamaicense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 38. Outgoing r'ship FOUND_IN to/from Swertia Hickinii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 39. Outgoing r'ship FOUND_IN to/from Tarenna Asiatica (Plant) Rel Props:Reference:ISBN:9780387706375
  • 40. Outgoing r'ship FOUND_IN to/from Trachyspermum Ammi (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172361150
  • 41. Outgoing r'ship FOUND_IN to/from Trifolium Alexandrinum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all