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Periplogenin

PubChem CID: 10574

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Compound Synonyms Periplogenin, 514-39-6, Desoxostrophanthidin, 5-beta-Hydroxydigitoxigenin, 5.beta.-Hydroxydigitoxigenin, UNII-B6808P7IY9, 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, B6808P7IY9, PERIPLOGENIN [MI], 3-beta,5,14-Trihydroxy-5-beta-card-20(22)-enolide, 5-beta-CARD-20(22)-ENOLIDE, 3-beta,5,14-TRIHYDROXY-, Card-20(22)-enolide, 3,5,14-trihydroxy-, (3-beta,5-beta)-, Card-20(22)-enolide, 3,5,14-trihydroxy-, (3.beta.,5.beta.)-, 3.beta.,5.beta.,14.beta.-Trihydroxy-20(22)-cardenolide, 5.beta.-Card-20(22)-enolide, 3.beta.,5,14-trihydroxy-, (3.BETA.,5.BETA.)-3,5,14-TRIHYDROXYCARD-20(22)-ENOLIDE, 3-((3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-17-yl)-2H-furan-5-one, MFCD01745139, 5beta-Hydroxydigitoxigenin, CHEMBL460768, SCHEMBL1483841, DTXSID50965711, HY-N2414, s9168, AKOS015897157, CCG-268535, AC-34247, DA-56703, FP167441, MS-26510, 3,5,14-Trihydroxycard-20(22)-enolide, 1ST174296, 3,5,14-Trihydroxycard-20(22)-enolide #, CS-0022615, NS00093752, 3beta,5beta,14beta-Trihydroxy-20(22)-cardenolide, 5beta-Card-20(22)-enolide, 3beta,5,14-trihydroxy-, Q27274425, (3beta,5beta)-3,5,14-trihydroxycard-20(22)-enolide, Card-20(22)-enolide, 3,5,14-trihydroxy-, (3beta,5beta)-, Card-20(22)-enolide, 3,5,14-trihydroxy-, (3-beta,5-beta)-(9CI)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 87.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C2CCC3C2CCC2C4CCCCC4CCC23)C1
Np Classifier Class Cardenolides
Deep Smiles O[C@H]CC[C@][C@]C6)O)CC[C@@H][C@@H]6CC[C@][C@]6O)CC[C@@H]5C=CC=O)OC5)))))))))C)))))))))C
Heavy Atom Count 28.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 733.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.1
Gsk 4 400 Rule True
Molecular Formula C23H34O5
Scaffold Graph Node Bond Level O=C1C=C(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Prediction Swissadme 1.0
Inchi Key QJPCKAJTLHDNCS-FBAXFMHRSA-N
Silicos It Class Soluble
Fcsp3 0.8695652173913043
Logs -3.584
Rotatable Bond Count 1.0
Logd 1.928
Synonyms periplogenin
Esol Class Soluble
Functional Groups CC1=CC(=O)OC1, CO
Compound Name Periplogenin
Prediction Hob Swissadme 1.0
Exact Mass 390.241
Formal Charge 0.0
Monoisotopic Mass 390.241
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 390.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.913424000000001
Inchi InChI=1S/C23H34O5/c1-20-7-3-15(24)12-22(20,26)9-5-18-17(20)4-8-21(2)16(6-10-23(18,21)27)14-11-19(25)28-13-14/h11,15-18,24,26-27H,3-10,12-13H2,1-2H3/t15-,16+,17-,18+,20+,21+,22-,23-/m0/s1
Smiles C[C@]12CC[C@@H](C[C@]1(CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O)O
Nring 5.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

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  • 2. Outgoing r'ship FOUND_IN to/from Erysimum Repandum (Plant) Rel Props:Reference:ISBN:9788172360481; ISBN:9788185042084
  • 3. Outgoing r'ship FOUND_IN to/from Lagenaria Siceraria (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/21287437
  • 4. Outgoing r'ship FOUND_IN to/from Panax Ginseng (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/8768321
  • 5. Outgoing r'ship FOUND_IN to/from Periploca Sepium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Streptocaulon Juventas (Plant) Rel Props:Source_db:cmaup_ingredients