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Cryptophycin 28

PubChem CID: 10508182

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Compound Synonyms Cryptophycin 28, Cryptophycin-28, (3S,6R,10R,13E,16R)-10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-16-[(E)-3-phenylprop-2-enyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,6R,10R,13E,16R)-10-((3-chloro-4-methoxyphenyl)methyl)-6-methyl-3-(2-methylpropyl)-16-((E)-3-phenylprop-2-enyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, 168482-39-1, CHEMBL266856, CHEBI:217640, YMZVKVLSUBCSND-DWEOSBBHSA-N, DTXSID301046177
Topological Polar Surface Area 120.0
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 44.0
Isotope Atom Count 0.0
Molecular Complexity 1010.0
Database Name cmaup_ingredients;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (3S,6R,10R,13E,16R)-10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-16-[(E)-3-phenylprop-2-enyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
Prediction Hob 0.0
Xlogp 6.7
Molecular Formula C34H41ClN2O7
Prediction Swissadme 0.0
Inchi Key YMZVKVLSUBCSND-DWEOSBBHSA-N
Fcsp3 0.4117647058823529
Logs -5.462
Rotatable Bond Count 8.0
Logd 3.805
Compound Name Cryptophycin 28
Prediction Hob Swissadme 0.0
Exact Mass 624.26
Formal Charge 0.0
Monoisotopic Mass 624.26
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 625.1
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 2.0
Esol -7.944722581818183
Inchi InChI=1S/C34H41ClN2O7/c1-22(2)18-30-34(41)43-26(13-8-12-24-10-6-5-7-11-24)14-9-15-31(38)37-28(32(39)36-21-23(3)33(40)44-30)20-25-16-17-29(42-4)27(35)19-25/h5-12,15-17,19,22-23,26,28,30H,13-14,18,20-21H2,1-4H3,(H,36,39)(H,37,38)/b12-8+,15-9+/t23-,26-,28-,30+/m1/s1
Smiles C[C@@H]1CNC(=O)[C@H](NC(=O)/C=C/C[C@H](OC(=O)[C@@H](OC1=O)CC(C)C)C/C=C/C2=CC=CC=C2)CC3=CC(=C(C=C3)OC)Cl
Nring 3.0
Defined Bond Stereocenter Count 2.0

  • 1. Outgoing r'ship FOUND_IN to/from Ajuga Nipponensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Eriobotrya Deflexa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Grevillea Robusta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Neurolaena Lobata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all