This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration. This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration.

7-Ethyl-10-hydroxycamptothecin

PubChem CID: 104842

Connections displayed (default: 10).
Loading graph...

Compound Synonyms 7-Ethyl-10-hydroxycamptothecin, 86639-52-3, SN-38, SN 38 lactone, SN 38, 7-Ethyl-10-hydroxy-camptothecin, (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-Hydroxy-7-ethylcamptothecin, SN38, 7-Ethyl-10-hydroxy-20(S)-camptothecin, NK 012, NK-012, NK012, CHEBI:8988, (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione, 113015-38-6, IT-141, NSC673596, 0H43101T0J, (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, CAMPTOTHECIN, 7-ETHYL-10-HYDROXY-, (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, MFCD00871873, 7-ethyl-10-hydroxy-20(s)-campthothecin, LE-SN38, Captothecin, 7-ethyl-10-hydroxy-, UNII-0H43101T0J, C22H20N2O5, 1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4,11-DIETHYL-4,9-DIHYDROXY-, (4S)-, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-, AvaChem1025, SN-38 (Standard), (+)-7-ETHYL-10-HYDROXYCAMPTOTHECIN, diethyl(dihydroxy)[?]dione, SCHEMBL34018, GTPL6925, SN 38 [WHO-DD], DTXSID4040399, 10-hydroxy-7-ethyl camptothecin, 10-hydroxy-7-ethyl-camptothecin, EX-A989, HMS3413B12, HMS3652P12, HMS3677B12, HMS3753E15, BCP01386, 7-Ethyl-10-hydroxy-20(S)-CPT, BDBM50418088, HY-13704R, s4908, AKOS015920433, AC-1357, BCP9000200, CCG-264764, CS-1579, DB05482, FE29579, NSC-673596, SN-38(NK-012)?, NCGC00167831-01, NCGC00167831-05, 110714-48-2, AS-13533, BP-24513, HY-13704, NCI60_026056, 7-Ethyl-10-hydroxy-20-(S)-camptothecine, E0748, NS00069821, SW219948-1, S-(+)-7-ETHYL-10-HYDROXYCAMPOTHECIN, EN300-122379, Q1750127, BRD-K89561498-001-01-7, BRD-K89561498-001-02-5, 7-Ethyl-10-hydroxycamptothecin, >=98% (HPLC), powder, Z1541759909, (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione, AldrichCPR, (S)-4,11-Diethyl-4,9-di-OH-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione, 1H-Pyrano[3',7]indolizino[1,2-b]quinoline- 3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-, 7-Ethyl-10-hydroxycamptothecin ((S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione), H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (S)-, RS4
Topological Polar Surface Area 100.0
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 29.0
Isotope Atom Count 0.0
Molecular Complexity 820.0
Database Name cmaup_ingredients;hmdb_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Uniprot Id Q9BY64, P06133, P22310, P36537, P16662, P54855, Q9Y4X1, P22309, O60656, Q9HAW9, P35503, Q9HAW8, O75795, P19224, P35504, O75310, Q9HAW7, P23141, O00748, P08236, Q6UWM9
Iupac Name (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Prediction Hob 1.0
Class Camptothecins
Target Id NPT143, NPT109, NPT1422, NPT901
Xlogp 1.4
Superclass Alkaloids and derivatives
Molecular Formula C22H20N2O5
Prediction Swissadme 1.0
Inchi Key FJHBVJOVLFPMQE-QFIPXVFZSA-N
Fcsp3 0.3181818181818182
Logs -4.252
Rotatable Bond Count 2.0
Logd 1.577
Synonyms 10-Hydroxy-7-ethylcamptothecin, 7-Ethyl-10-hydroxy-20(S)-camptothecin, 7-Ethyl-10-hydroxycamptothecin, sn 38, sn 38 Lactone, CPT 11, Camptosar, Irrinotecan, Camptothecin-11, Irinotecan hydrochloride, CPT-11, sn38 CPD, Irinotecan, NK012 Compound, CPT11, 7 Ethyl 10 hydroxycamptothecin, Camptothecin 11
Compound Name 7-Ethyl-10-hydroxycamptothecin
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 392.137
Formal Charge 0.0
Monoisotopic Mass 392.137
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 392.4
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Esol -4.514824062068966
Inchi InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1
Smiles CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O
Nring 5.0
Defined Bond Stereocenter Count 0.0
Taxonomy Direct Parent Camptothecins