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(1E,4E)-1-(4-Hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-1,4-pentadien-3-one

PubChem CID: 10469828

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Compound Synonyms 148625-88-1, (1E,4E)-1-(4-Hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-1,4-pentadien-3-one, CHEMBL2398585, SCHEMBL17019805, DTXSID101138794, (1e,4e)-1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxy phenyl-)-penta-1,4-dien-3-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 66.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1CCCCC1)CCC1CCCCC1
Np Classifier Class Linear diarylheptanoids
Deep Smiles COccc/C=C/C=O)/C=C/cccccc6))O))))))))))ccc6O
Heavy Atom Count 22.0
Classyfire Class Cinnamic acids and derivatives
Scaffold Graph Node Level OC(CCC1CCCCC1)CCC1CCCCC1
Classyfire Subclass Hydroxycinnamic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 407.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (1E,4E)-1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)penta-1,4-dien-3-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 3.5
Gsk 4 400 Rule True
Molecular Formula C18H16O4
Scaffold Graph Node Bond Level O=C(C=Cc1ccccc1)C=Cc1ccccc1
Prediction Swissadme 0.0
Inchi Key QVRYUUYYIWAQHV-LUZURFALSA-N
Silicos It Class Moderately soluble
Fcsp3 0.0555555555555555
Logs -3.581
Rotatable Bond Count 5.0
Logd 3.359
Synonyms 1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydoxyphenyl)-penta-(1e,4e)-1,4-dien-3-one
Esol Class Soluble
Functional Groups c/C=C/C(=O)/C=C/c, cO, cOC
Compound Name (1E,4E)-1-(4-Hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-1,4-pentadien-3-one
Prediction Hob Swissadme 0.0
Exact Mass 296.105
Formal Charge 0.0
Monoisotopic Mass 296.105
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 296.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 2.0
Lipinski Rule Of 5 True
Esol -3.930632763636364
Inchi InChI=1S/C18H16O4/c1-22-18-12-14(6-11-17(18)21)5-10-16(20)9-4-13-2-7-15(19)8-3-13/h2-12,19,21H,1H3/b9-4+,10-5+
Smiles COC1=C(C=CC(=C1)/C=C/C(=O)/C=C/C2=CC=C(C=C2)O)O
Nring 2.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 2.0
Egan Rule True
Np Classifier Superclass Diarylheptanoids

  • 1. Outgoing r'ship FOUND_IN to/from Curcuma Longa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Dioscorea Nipponica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all